Autism is a heterogeneous neurodevelopmental disorder of unknown aetiology that affects 1
in 100–150 individuals. Diagnosis is based on three categories of behavioural criteria …

Animal models provide preclinical tools to investigate the causal role of genetic mutations
and environmental factors in the etiology of autism spectrum disorder (ASD). Knockout and …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

Mood and anxiety disorders are prevalent conditions affecting one out of four people during
lifetime. The development of high validity animal models to study these disorders has been a …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models …

Various tests have been developed to evaluate behavior in animal studies where rodents
are used as animal models. These tests are useful for understanding the pathophysiology of …

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability in
humans. In addition to cognitive impairment, patients may exhibit hyperactivity, attention …

Stress plays a key role in pathogenesis of anxiety and depression. Animal models of these
disorders are widely used in behavioral neuroscience to explore stress-evoked brain …

The link between social factors, stress and health has been the focus of many
interdisciplinary studies mostly because:(i) animals, including humans, often live in …

Autism spectrum disorder (ASD) is a highly heritable, clinically diverse group of
neurodevelopmental disorders. Its genetic heterogeneity is remarkable, with more than 800 …