Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …

Sonodynamic therapy (SDT) has been proposed as a new modality for cancer management
through low-intensity ultrasound induced activation of sonosensitizers. Here, we designed a …

Paclitaxel (PTX) is a broad‐spectrum alkaloid anticancer drug with high therapeutic efficacy.
However, PTX has a very low water solubility and its metabolism demonstrates nonlinear …

Resveratrol (RSV) is a natural product with multiple biological benefits including anticancer
properties. Unfortunately, its biological benefits are limited by its low bioavailability and rapid …

Breast cancer is among the most prevalent malignancies, accounting for 685,000 deaths
worldwide in 2020, largely due to its high metastatic potential. Depending on the stage and …

Deformable materials have garnered widespread attention in biomedical applications.
Herein, a controllable, general, and simple alkaline etching strategy was used to synthesize …

Peritoneal mesothelioma is an aggressive disease with a median survival of under three
years, due to a lack of effective treatment options. Mesothelioma is traditionally considered a …

Drug delivery to the esophagus through systemic administration remains challenging, as
minimal drug reaches the desired target. Local delivery offers the potential for improved …

Cells can sense the mechanical stimulation of nanoparticles (NPs) and then regulate the
cellular uptake process. The enhanced endocytosis efficiency can improve the concentration …

Abstract Poly (amide-imide) s (PAIs) present limited use in bioapplications due to their poor
aqueous solubility and difficulty in functional accessibility. Herein, we prepared PAI-based …