Identifying the genetic factors that underlie complex traits is central to understanding the
mechanistic underpinnings of evolution. Cave-dwelling Astyanax mexicanus populations …

Dual specificity phosphatases (DUSPs) play a crucial role in the regulation of intracellular
signalling pathways, which in turn influence a broad range of physiological processes …

Maintaining normal cellular behavior is essential for the survival of organisms. One of the
main mechanisms to control cellular behavior is protein phosphorylation. The process of …

Peristaltic movement of the intestine propels food down the length of the gastrointestinal
tract to promote nutrient absorption. Interactions between intestinal macrophages and the …

Abstract Dual-specificity Phosphatases (DUSPs) are not only the key regulators of
dephosphorylating and inactivating mitogen-activated protein kinases (MAPKs), but play a …

Several enzymes are capable of producing reactive oxygen species (ROS), but only NADPH
oxidases (NOX) generate ROS as their primary and sole function. In the central nervous …

Cells encounter a myriad of endogenous and exogenous stresses that could perturb cellular
physiological processes. Therefore, cells are equipped with several adaptive and stress …

Abstract Dual-specificity phosphatase 26 (DUSP26) is linked to a broad range of human
disorders as it affects numerous signaling cascades. However, the involvement of DUSP26 …

Dual-specificity phosphatases (DUSPs) are important regulators of neuronal cell growth and
differentiation by targeting proteins essential to neuronal survival in signaling pathways …

Parkinson's disease (PD), characterized by dopaminergic neuron degeneration in the
substantia nigra and dopamine depletion in the striatum, affects up to 1% of the global …