Chitosan-coated nanoparticles: Effect of chitosan molecular weight on nasal transmucosal delivery
FA Bruinsmann, S Pigana, T Aguirre, G Dadalt Souto… - Pharmaceutics, 2019 - mdpi.com
Drug delivery to the brain represents a challenge, especially in the therapy of central
nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential …
nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential …
The use of chitosan as cationic coating or gel vehicle for polymeric nanocapsules: Increasing penetration and adhesion of imiquimod in vaginal tissue
LA Frank, PS Chaves, CM D'Amore, RV Contri… - European Journal of …, 2017 - Elsevier
The human papillomavirus (HPV) infection, which is strongly related to cervical cancer, can
be reduced by the topical application of imiquimod. Some strategies have been used to …
be reduced by the topical application of imiquimod. Some strategies have been used to …
[HTML][HTML] Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis
A Torge, S Wagner, PS Chaves, EG Oliveira… - International journal of …, 2017 - Elsevier
Abstract Treatment of bacterial airway infections is essential for cystic fibrosis therapy.
However, effectiveness of antibacterial treatment is limited as bacteria inside the mucus are …
However, effectiveness of antibacterial treatment is limited as bacteria inside the mucus are …
Mucoadhesive properties of Eudragit® RS100, Eudragit® S100, and Poly (ε-caprolactone) nanocapsules: influence of the vehicle and the mucosal surface
PDS Chaves, LA Frank, AG Frank, AR Pohlmann… - Aaps Pharmscitech, 2018 - Springer
The use of polymers as mucoadhesive materials has been explored in several drug delivery
systems. It is well known that the resulting mucoadhesiveness not only depends on the …
systems. It is well known that the resulting mucoadhesiveness not only depends on the …
Innovative hydrogel containing polymeric nanocapsules loaded with phloretin: Enhanced skin penetration and adhesion
TPA Casarini, LA Frank, T Benin, G Onzi… - Materials Science and …, 2021 - Elsevier
Dermatological applications of phloretin are restricted by its poor aqueous solubility.
Nanotechnology has been proposed as strategy to increase the apparent drug solubility in …
Nanotechnology has been proposed as strategy to increase the apparent drug solubility in …
Imiquimod-loaded nanocapsules improve cytotoxicity in cervical cancer cell line
LA Frank, RP Gazzi, P de Andrade Mello… - European Journal of …, 2019 - Elsevier
This paper proposes the development of imiquimod-loaded polymeric nanocapsules
formulation for the treatment of cervical cancer. The mechanism of death involved in the …
formulation for the treatment of cervical cancer. The mechanism of death involved in the …
Chitosan-coated dapsone-loaded lipid-core nanocapsules: Growth inhibition of clinical isolates, multidrug-resistant Staphylococcus aureus and Aspergillus ssp.
R Cé, JG Marchi, VZ Bergamo, AM Fuentefria… - Colloids and Surfaces A …, 2016 - Elsevier
Abstract Lecithin-polysorbate 80-lipid-core nanocapsules (LNC) or chitosan-coated LNC
(LNC-CS) containing or not dapsone (DAP) were prepared and characterized. Particle size …
(LNC-CS) containing or not dapsone (DAP) were prepared and characterized. Particle size …
Nanoemulsification of Essential Oil Blend by Ultrasound: Optimization of Physicochemical, Antioxidant Properties, and Activity Against Escherichia coli
This study aimed to select the best conditions for producing a nanoemulsion loaded with an
essential oil blend (NEOB) to achieve maximum antimicrobial and antioxidant activities. The …
essential oil blend (NEOB) to achieve maximum antimicrobial and antioxidant activities. The …
Determining suitable region wind speed probability distribution using optimal score-radar map
Determination of wind speed probability distribution is of considerable importance to the
accurate wind energy assessment. This paper proposes an optimal score-radar map for …
accurate wind energy assessment. This paper proposes an optimal score-radar map for …
Erlotinib-Loaded Poly(ε-Caprolactone) Nanocapsules Improve In Vitro Cytotoxicity and Anticlonogenic Effects on Human A549 Lung Cancer Cells
FA Bruinsmann, JH Buss, GD Souto, E Schultze… - AAPS …, 2020 - Springer
Lung cancer is the most frequent type of cancer and the leading cause of cancer-related
mortality worldwide. This study aimed to develop erlotinib (ELB)-loaded poly (ε …
mortality worldwide. This study aimed to develop erlotinib (ELB)-loaded poly (ε …