[HTML][HTML] The impact of oxidative stress on male reproductive function: Exploring the role of antioxidant supplementation

G Walke, SS Gaurkar, R Prasad, T Lohakare… - Cureus, 2023 - ncbi.nlm.nih.gov
Male reproductive function is highly susceptible to oxidative stress, which arises from an
imbalance between reactive oxygen species (ROS) production and antioxidant defense …

Oxidative stress in male infertility and therapeutic approach: A mini-review

M Lahimer, H Mustapha, V Bach… - Asian Pacific Journal …, 2023 - journals.lww.com
Growing evidence suggests that oxidative stress is a major cause of male infertility.
Spermatozoa are highly sensitive cells due to the vulnerability of their membrane fatty acids …

COVID-19 associates with semen inflammation and sperm quality impairment that reverses in the short term after disease recovery

MS Martinez, FN Ferreyra, DA Paira, VE Rivero… - Frontiers in …, 2023 - frontiersin.org
Introduction: COVID-19 exerts deleterious effects on the respiratory, cardiovascular,
gastrointestinal, and central nervous systems, causing more severe disease in men than in …

Sperm mitochondrial content and mitochondrial DNA to nuclear DNA ratio are associated with body mass index and progressive motility

E Moustakli, A Zikopoulos, C Skentou, I Bouba… - Biomedicines, 2023 - mdpi.com
Background: Mitochondrial dysfunction is a risk factor in the pathogenesis of metabolic
disorders. According to the energy requirements, oxidative phosphorylation and the electron …

Omega-3 fatty acid ameliorates bisphenol F-induced testicular toxicity by modulating Nrf2/NFkB pathway and apoptotic signaling

AF Odetayo, WJ Adeyemi, LA Olayaki - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Bisphenol F (BPF) has been shown to disrupt testicular functions via
perturbation of testicular redox balance, while omega-3 fatty acid (O3FA) has been …

Effect of antioxidants on semen parameters in men with oligo‐astheno‐teratozoospermia: a network meta‐analysis

A Barbonetti, D Tienforti, C Castellini, FD Giulio… - …, 2024 - Wiley Online Library
Background Although antioxidants are largely used in subfertile men with oligo‐astheno‐
teratozoospermia (OAT), the choice among different molecules is challenged by the lack of …

Effect of Micronutrients and L-Carnitine as Antioxidant on Sperm Parameters, Genome Integrity, and ICSI Outcomes: Randomized, Double-Blind, and Placebo …

M Lahimer, O Gherissi, N Ben Salem, H Ben Mustapha… - Antioxidants, 2023 - mdpi.com
The evaluation of sperm DNA integrity is recommended in the sixth edition of the 2021 World
Health Organization guidelines. Oxidative stress has been identified as a crucial factor …

Omega-3 fatty acids abrogates oxido-inflammatory and mitochondrial dysfunction-associated apoptotic responses in testis of tamoxifen-treated rats

AF Odetayo, RE Akhigbe, MA Hamed… - Frontiers in …, 2024 - frontiersin.org
Background Tamoxifen (TAM) is a widely used drug in patients with gynecomastia and
breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately …

Testicular and haematological cancer induce very high levels of sperm oxidative stress

C Calamai, O Ammar, V Rosta, G Farnetani, S Zimmitti… - Antioxidants, 2023 - mdpi.com
Cancer impairs spermatogenesis, whereas results on sperm DNA integrity are controversial
and no data are available about sperm oxidative stress. In cancer patients, we detected …

Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining …

KB Okesina, AF Odetayo, WJ Adeyemi… - Laboratory Animal …, 2024 - Springer
Background Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs,
including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility …