Exercise as a positive modulator of brain function

KA Alkadhi - Molecular neurobiology, 2018 - Springer
Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …

Molecular, neurochemical, and behavioral hallmarks of reserpine as a model for Parkinson's disease: new perspectives to a long‐standing model

AHFF Leão, AJ Sarmento‐Silva, JR Santos… - Brain …, 2015 - Wiley Online Library
The administration of reserpine to rodents was one of the first models used to investigate the
pathophysiology and screening for potential treatments of P arkinson's disease (PD). The …

Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's disease

VS Fernandes, JR Santos, AHFF Leão… - Behavioural Brain …, 2012 - Elsevier
Animal models are widely used to study alterations caused by Parkinson's disease (PD).
However, in general, pharmacological models do not express the progressive nature of the …

Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP+ toxicity

YH Tsou, CT Shih, CH Ching, JY Huang, CJ Jen… - Experimental …, 2015 - Elsevier
Exercise induces oxidative stress, which may activate adaptive antioxidant responses.
Nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in the defense of …

Gallic acid prevents ketamine-induced oxidative damages in brain regions and liver of rats

PI Schimites, HJ Segat, LG Teixeira, LR Martins… - Neuroscience …, 2020 - Elsevier
Introduction Ketamine (KET) is an anesthetic agent widely used in human and veterinary
medicine. According to studies, KET is associated to direct neutorotoxic damages due to its …

Repeated treatment with a low dose of reserpine as a progressive model of Parkinson's dementia.

H Ikram, DJ Haleem - Pakistan Journal of Pharmaceutical …, 2019 - search.ebscohost.com
Present study was designed to monitor the cognitive profile of the animals upon repeated
administration of reserpine, so as to determine that whether these animals should be used …

Could dietary trans fatty acids induce movement disorders? Effects of exercise and its influence on Na+ K+-ATPase and catalase activity in rat striatum

AM Teixeira, VT Dias, CS Pase, K Roversi… - Behavioural brain …, 2012 - Elsevier
The influence of trans fatty acids (FA) on development of orofacial dyskinesia (OD) and
locomotor activity was evaluated. Rats were fed with diets enriched with 20% soybean oil …

Comparative study between two animal models of extrapyramidal movement disorders: prevention and reversion by pecan nut shell aqueous extract

F Trevizol, DM Benvegnú, RCS Barcelos… - Behavioural brain …, 2011 - Elsevier
Acute reserpine and subchronic haloperidol are animal models of extrapyramidal disorders
often used to study parkinsonism, akinesia and tardive dyskinesia. In humans, these usually …

Exercise modifies amphetamine relapse: behavioral and oxidative markers in rats

HJ Segat, M Kronbauer, K Roversi, AJ Schuster… - Behavioural brain …, 2014 - Elsevier
Exercise has been reported to attenuate rewarding symptoms related to addictive drugs
mainly by affecting the brain neuroplasticity and neurotransmission. In this study, we …

Endurance training on rodent brain antioxidant capacity: A meta-analysis

RF de Souza, SRA de Moraes, RL Augusto… - Neuroscience …, 2019 - Elsevier
The influence of physical exercise on brain antioxidant defense mechanisms has been
studied. Nevertheless, the effect of training volume on the brains redox balance remains …