A review of cyclic olefin copolymer applications in microfluidics and microdevices

A Agha, W Waheed, N Alamoodi… - Macromolecular …, 2022 - Wiley Online Library
Cyclic olefin copolymers (COC) are amorphous, transparent thermoplastics composed of
cyclic olefin monomers (norbornene) and linear olefins (ethene). They are increasingly …

Development of lab-on-chip biosensor for the detection of toxic heavy metals: A review

V Karthik, B Karuna, PS Kumar, A Saravanan… - Chemosphere, 2022 - Elsevier
Recently, a decrease in water availability and quality has been raised due to rapid
industrialization, unsustainable agricultural activities and anthropogenic activities. Heavy …

[HTML][HTML] Electro-discharge machining of ceramics: A review

A Bilal, MP Jahan, D Talamona, A Perveen - Micromachines, 2018 - mdpi.com
Conventional machining techniques of ceramics such as milling, drilling, and turning
experience high cutting forces as well as extensive tool wear. Nevertheless, non-contact …

Rapid prototyping of whole-thermoplastic microfluidics with built-in microvalves using laser ablation and thermal fusion bonding

SAM Shaegh, A Pourmand, M Nabavinia, H Avci… - Sensors and Actuators B …, 2018 - Elsevier
Recently, there has been an increasing effort in developing new fabrication methods for
rapid prototyping of microfluidic chips using thermoplastic materials. This is mainly due to …

[HTML][HTML] WEDM as a Replacement for Grinding in Machining Ceramic Al2O3-TiC Cutting Inserts

SN Grigoriev, AB Nadykto, MA Volosova, AA Zelensky… - Metals, 2021 - mdpi.com
Small-size cutting inserts for assembly cutters are widely used to manufacture a variety of
parts for the aerospace, automotive and mechanical engineering industries. Due to their …

[HTML][HTML] On-chip modeling of tumor evolution: Advances, challenges and opportunities

C Li, JB Holman, Z Shi, B Qiu, W Ding - Materials Today Bio, 2023 - Elsevier
Tumor evolution is the accumulation of various tumor cell behaviors from tumorigenesis to
tumor metastasis and is regulated by the tumor microenvironment (TME). However, the …

Rapid fabrication of a four-layer PMMA-based microfluidic chip using CO2-laser micromachining and thermal bonding

X Chen, J Shen, M Zhou - Journal of Micromechanics and …, 2016 - iopscience.iop.org
A smart design method to transform the original two-layer microfluidic chip into a four-layer
3D microfluidic chip is proposed. A novel fabrication method is established to rapidly and …

Assessment of PMMA and polystyrene based microfluidic chips fabricated using CO2 laser machining

I Bilican, MT Guler - Applied Surface Science, 2020 - Elsevier
Laser machining could be an alternative way for the fabrication of microchannels. In this
study, laser machining of polymethylmethacrylate (PMMA) and polystyrene (PS) substrates …

[HTML][HTML] Analysis of wire-cut electro discharge machining of polymer composite materials

TR Ablyaz, ES Shlykov, KR Muratov, SS Sidhu - Micromachines, 2021 - mdpi.com
This study presents the analysis of wire-cut electro-discharge machining (WIRE-EDM) of
polymer composite material (PCM). The conductivity of the workpiece is improved by using 1 …

[HTML][HTML] Safe and cost-effective rapid-prototyping of multilayer PMMA microfluidic devices

A Liga, JAS Morton, M Kersaudy-Kerhoas - Microfluidics and Nanofluidics, 2016 - Springer
The rapid translation of research from bench to bedside, as well as the generation of
commercial impact, has never been more important for both academic and industrial …