Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …

Introduction Although rare, pediatric severe therapy-resistant asthma (STRA) is a highly
heterogeneous, resource-demanding disease that differs significantly from severe adult …

Simple Summary Severe equine asthma (sEA) is a highly prevalent respiratory disease
affecting adult horses. Affected horses present with cough, nasal discharge and increased …

Neutrophil extracellular traps (NETs) are a recently described mechanism of neutrophils that
play an important role in health and disease. NETs are an innate defense mechanism that …

Asthma is a chronic disease of the airways that has an important inflammatory component.
Multiple cells are implicated in asthma pathogenesis (lymphocytes, eosinophils, mast cells …

Severe equine asthma (SEA) is a complex respiratory condition characterized by chronic
airway inflammation. It shares many clinical and pathological features with human …

Companion animals in veterinary medicine develop multiple naturally occurring diseases
analogous to human conditions. We previously reported a comprehensive review on the …

Background Studies in adult severe treatment-resistant asthma (STRA) have demonstrated
heterogeneous pathophysiology. Studies in the pediatric age group are still scarce, and few …

Horses have many naturally occurring diseases that mimic similar conditions in humans.
The ability to conduct environmentally controlled experiments and induced disease studies …

Objectives Aeroallergens have been discussed as potential triggers for feline asthma (FA),
which can be induced experimentally by allergen sensitization. To date, only few studies …