This article discusses three aspects of inner filter effect (IFE) in fluorescence spectroscopy.(i)
First, IFE as undesirable in fluorescence measurements: IFE results in non-linear …

Optical sensing of specific molecular targets and pathways deep inside living mice has
become possible as a result of a number of advances. These include design of …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

During the development of neoplasia, epithelial tissues undergo biochemical and structural
changes that can manifest in tissue fluorescence. There have been several reports on …

Background Enzyme assays have widespread applications in drug discovery from plants to
natural products. The appropriate use of blanks in enzyme assays is important for assay …

BACKGROUND Understanding the development and progression of head and neck
squamous cell carcinoma is key in the quest for the early diagnosis and prevention of this …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …

This paper reviews the recent developments in the field of biomedical optical imaging,
emphasizing technologies that have been moved from'bench top to bedside'. Important new …

We present a novel fluorescence imaging system developed for real-time interventional
imaging applications. The system implements a correction scheme that improves the …

We present a method for tissue fluorescence quantification in situ using a handheld fiber
optic probe that measures both the fluorescence and diffuse reflectance spectra. A simplified …