The American Diabetes Association (ADA) and the European Association for the Study of
Diabetes (EASD) convened a writing group to develop a consensus statement on the …

Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

These preliminary data from an ongoing first-in-human phase 1/2, open-label study provide
proof-of-concept that pluripotent stem cell-derived pancreatic endoderm cells (PEC-01) …

Human pluripotent stem-cell-derived islets (hPSC-islets) are a promising cell resource for
diabetes treatment,. However, this therapeutic strategy has not been systematically …

The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to
reduce disease complications. For some patients, technological approaches to insulin …

Since its introduction more than twenty years ago, intraportal allogeneic cadaveric islet
transplantation has been shown to be a promising therapy for patients with Type I Diabetes …

HANDBOOK OF DIABETES The Handbook of Diabetes provides concise and efficient
coverage of the diagnosis, epidemiology, and management of diabetes and its …

Background Allogeneic islet transplantation is a validated therapy in type 1 diabetes;
however, there is decline of transplanted islet graft function over time and the mechanisms …

Whole-organ pancreas and islet transplantations are performed in a highly selected group of
patients with diabetes mellitus, primarily those with type 1 diabetes mellitus, complicated by …

Aims/hypothesis Islet transplantation has been studied in small cohorts of recipients with
type 1 diabetes complicated by severe hypoglycaemic events (SHEs). We determined …