Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

Comprising the majority of leukocytes in humans, neutrophils are the first immune cells to
respond to inflammatory or infectious etiologies and are crucial participants in the proper …

Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

Liposomes are emerging cargoes for bioactive delivery owing to their widely accepted
biocompatible and biodegradable nature. It is always a challenge to control the release of …

Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …

Antimicrobial peptides (AMPs) have been studied for three decades, and yet a molecular
understanding of their mechanism of action is still lacking. Here we summarize current …

Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …

Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

The production of natural antibiotic peptides has emerged as an important mechanism of
innate immunity in plants and animals. Defensins are diverse members of a large family of …

The neutrophil is a major effector cell of innate immunity. Exocytosis of granules and
secretory vesicles plays a pivotal role in most neutrophil functions from early activation to the …