Can we construct a model of brain function that enables an understanding of whole-brain
circuit mechanisms underlying neurological disease and use it to predict the outcome of …

Altered or atypical functional connectivity as measured with functional magnetic resonance
imaging (fMRI) is a hallmark feature of brain connectopathy in psychiatric, developmental …

Noradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity
in neuronal networks across the brain, modulating multiple behavioral states. NA release is …

Schizophrenia (SCZ) is a highly heterogeneous disorder with diverse clinical manifestations
and macro-and microscale biological variations, usually observed at dissociable levels …

While humans are known to have several premotor cortical areas, secondary motor cortex
(M2) is often considered to be the only higher-order motor area of the mouse brain and is …

Quantifying emotional aspects of animal behavior (eg, anxiety, social interactions, reward,
and stress responses) is a major focus of neuroscience research. Because manual scoring …

The striatum, known as the input nucleus of the basal ganglia, is extensively studied for its
diverse behavioral roles. However, the relationship between its neuronal and vascular …

Sensory processing is a complex neurological process that receives, integrates, and
responds to information from one's own body and environment, which is closely related to …

While deep brain stimulation (DBS) is widely employed for managing motor symptoms in
Parkinson's disease (PD), its exact circuit mechanisms remain controversial. To identify the …

The dorsal striatum is instrumental in regulating motor control and goal-directed behaviors.
The classical description of the two output pathways of the dorsal striatum highlights their …