Repurposing molecular imaging and sensing for cancer image–guided surgery

SB Mondal, CM O'Brien, K Bishop… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Gone are the days when medical imaging was used primarily to visualize anatomic
structures. The emergence of molecular imaging (MI), championed by radiolabeled 18F …

Emerging clinical applications in oncology for non‐invasive multi‐and hyperspectral imaging of cell and tissue autofluorescence

JM Campbell, A Habibalahi, S Handley… - Journal of …, 2023 - Wiley Online Library
Hyperspectral and multispectral imaging of cell and tissue autofluorescence is an emerging
technology in which fluorescence imaging is applied to biological materials across multiple …

Optical signatures derived from deep UV to NIR excitation discriminates healthy samples from low and high grades glioma

H Mehidine, A Chalumeau, F Poulon, F Jamme… - Scientific Reports, 2019 - nature.com
Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …

Molecular changes tracking through multiscale fluorescence microscopy differentiate Meningioma grades and non-tumoral brain tissues

H Mehidine, M Refregiers, F Jamme, P Varlet… - Scientific reports, 2021 - nature.com
Meningioma is the most common primary intracranial extra-axial tumor. Total surgical
removal is the standard therapeutic method to treat this type of brain tumors. However, the …

[HTML][HTML] Theoretical platform for liquid-crystalline self-assembly of collagen-based biomaterials

SA Khadem, AD Rey - Frontiers in Physics, 2019 - frontiersin.org
The collagen triple helix is a ubiquitous biomacromolecule used in acidic aqueous solutions
as precursor in the fabrication of artificial compact bone and cornea and in tissue …

Computer-aided multiphoton microscopy diagnosis of five different primary architecture subtypes of meningiomas

N Fang, Z Wu, X Su, R Chen, L Shi, Y Feng… - Laboratory …, 2024 - Elsevier
Meningiomas rank among the most common intracranial tumors, and surgery stands as the
primary treatment modality for meningiomas. The precise subtyping and diagnosis of …

[HTML][HTML] Comparative Study Between a Customized Bimodal Endoscope and a Benchtop Microscope for Quantitative Tissue Diagnosis

H Mehidine, B Devaux, P Varlet, D Abi Haidar - Frontiers in Oncology, 2022 - frontiersin.org
Nowadays, surgical removal remains as the standard method to treat brain tumors. During
surgery, the neurosurgeon may encounter difficulties to delimitate tumor boundaries and the …

Comparison of optically‐derived biomarkers in healthy and brain tumor tissue under one‐and two‐photon excitation

M Sibai, H Mehidine, EK Moawad… - Journal of …, 2019 - Wiley Online Library
The surgical outcome of brain tumor resection and needle biopsy is significantly correlated
to the patient's prognosis. Brain tumor surgery is limited to resecting the solid portion of the …

Automatic and label-free detection of meningioma in dura mater using the combination of multiphoton microscopy and image analysis

N Fang, Z Wu, R Chen, Z Chen, L Zheng… - …, 2023 - spiedigitallibrary.org
Significance To prevent meningioma recurrence, it is necessary to detect and remove all
corresponding tumors intraoperatively, including those in the adjacent dura mater. Aim …

[PDF][PDF] Classification of Brain Tumour Tissues in Human Patients using Machine Learning.

F Bouvet, H Mehidine, B Devaux, P Varlet… - …, 2022 - scitepress.org
Delineating brain tumor margins as accurately as possible is a challenge faced by the
neurosurgeon during tumor resections. The extent of resection is correlated with the survival …