Learning and memory rely on long-lasting, synapse-specific modifications. Although
postsynaptic forms of plasticity typically require local protein synthesis, whether and how …

Synaptic connections between hippocampal mossy fibers (MFs) and CA3 pyramidal
neurons are essential for contextual memory encoding, but the molecular mechanisms …

Abstract The Fragile X syndrome (FXS) as the most common monogenetic cause of
cognitive impairment and autism indicates how tightly the dysregulation of synapse …

Synaptic cell-adhesion molecules (CAMs) organize the architecture and properties of neural
circuits. However, whether synaptic CAMs are involved in activity-dependent remodeling of …

Recent studies have indicated that Thymic stromal lymphopoietin (TSLP) plays an important
role in the prevention and treatment of asthma. However the role of TSLP in dysfunction of …

In the developing nervous system synaptic refinement, typified by the neuromuscular
junction where supernumerary connections are eliminated by axon retraction leaving the …

This chapter presents an emerging “case-based” system for decision-making that centers on
the retrieval of similar past episodes. It can be mathematically described by the economic …

Protein synthesis is crucial for solidifying long-term memories, likely by fine tuning synaptic
changes. Recent findings indicate that disruptions in synaptic protein synthesis may serve …

Hippokampale Moosfaser Boutons sind große, plastische Synapsen, die Körnerzellen aus
dem Gyrus dentatus mit CA3 Pyramidenzellen verbinden. Sie spielen eine substanzielle …

Neural circuits in mammalian brains consist of large numbers of different cell types having
different functional properties. To better understand the separate roles of individual neuron …