Quantification methods for viruses and virus-like particles applied in biopharmaceutical production processes
Introduction Effective cell-based production processes of virus particles are the foundation
for the global availability of classical vaccines, gene therapeutic vectors, and viral oncolytic …
for the global availability of classical vaccines, gene therapeutic vectors, and viral oncolytic …
Mechanistic modeling of viral particle production
Viral systems such as wild‐type viruses, viral vectors, and virus‐like particles are essential
components of modern biotechnology and medicine. Despite their importance, the …
components of modern biotechnology and medicine. Despite their importance, the …
Efficient simulation of viral transduction and propagation for biomanufacturing
The design of biomanufacturing platforms based on viral transduction and/or propagation
poses significant challenges at the intersection between synthetic biology and process …
poses significant challenges at the intersection between synthetic biology and process …
[HTML][HTML] Approximate moment methods for population balance equations in particulate and bioengineering processes
Population balance modeling is an established framework to describe the dynamics of
particle populations in disperse phase systems found in a broad field of industrial, civil, and …
particle populations in disperse phase systems found in a broad field of industrial, civil, and …
Anticipated cell lines selection in bioprocess scale-up through machine learning on metabolomics dynamics
G Barberi, A Benedetti, P Diaz-Fernandez, G Finka… - IFAC-PapersOnLine, 2021 - Elsevier
The development of biopharmaceutical therapeutics, such as monoclonal antibodies,
requires the testing of several cell lines at different development scales and the selection of …
requires the testing of several cell lines at different development scales and the selection of …
[HTML][HTML] Multi-Rate Data Fusion for State and Parameter Estimation in (Bio-) Chemical Process Engineering
For efficient operation, modern control approaches for biochemical process engineering
require information on the states of the process such as temperature, humidity or chemical …
require information on the states of the process such as temperature, humidity or chemical …
[PDF][PDF] Mathematical models of influenza A virus infection: Elucidating the impact of host cell factors and defective interfering particles on virus growth
T Laske - 2021 - pure.mpg.de
Influenza viruses, with the influenza A virus (IAV) being their most prominent representative,
are major human pathogens that pose an ongoing burden on global public health and …
are major human pathogens that pose an ongoing burden on global public health and …
[PDF][PDF] Multi-Rate Data Fusion for State and Parameter Estimation in (Bio-) Chemical Process Engineering. Processes 2021, 9, 1990
For efficient operation, modern control approaches for biochemical process engineering
require information on the states of the process such as temperature, humidity or chemical …
require information on the states of the process such as temperature, humidity or chemical …
[PDF][PDF] Mathematical models of influenza A virus infection: Elucidating the impact of host cell factors and defective interfering particles on virus growth
Influenza viruses, with the influenza A virus (IAV) being their most prominent representative,
are major human pathogens that pose an ongoing burden on global public health and …
are major human pathogens that pose an ongoing burden on global public health and …