Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

Introduction Asthma, allergic rhinitis, atopic dermatitis, and food allergy affect approximately
20% of the global population. Few studies describe the burden of the totality of these …

The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal
studies have indicated that allergic diseases occur in a time-based order: from atopic …

Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Objective To provide an overview of filaggrin biology and the role of filaggrin variants in
atopic dermatitis (AD) and allergic disease. Data Sources We performed a PubMed literature …

There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Food allergies are the result of immune responses that cause adverse reactions to foods.
Immune responses to foods may produce a spectrum of symptoms and disorders, including …

Background Although atopic dermatitis (AD) often presents in infancy and persists into
adulthood, comparative characterization of AD skin among different pediatric age groups is …

The incidence of allergic diseases is increasing, and research on their epidemiology,
pathophysiology, and the prevention of onset is urgently needed. The onset of allergic …