The NFAT family of transcription factors encompasses five proteins evolutionarily related to
the Rel/NFκB family (Chytil and Verdine 1996; Graef et al. 2001b). The primordial family …

The compilation of multiple metazoan genome sequences and the deluge of large-scale
expression data have combined to motivate the maturation of bioinformatics methods for the …

The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

Abstract Comparison of DNA sequences from different species is a fundamental method for
identifying functional elements in genomes. Here, we describe the VISTA family of tools …

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine
and drug development, having made inestimable contributions to human health. We report …

Presented here is a genome sequence of an individual human. It was produced from∼ 32
million random DNA fragments, sequenced by Sanger dideoxy technology and assembled …

It has been argued that the evolution of plant genome size is principally unidirectional and
increasing owing to the varied action of whole-genome duplications (WGDs) and mobile …

Serum response factor (SRF) is a widely expressed transcription factor involved in
orchestrating disparate programs of gene expression linked to muscle differentiation and …

In this work, we investigate morphological differences between Arabidopsis thaliana, which
has simple leaves, and its relative Cardamine hirsuta, which has dissected leaves …

Prediction of gene regulatory sequences using phylogenetic footprinting has advanced
considerably but lacks experimental validation. Here, we report whether transcription factor …