Recently, the pharmaceutical industry has been facing several challenges associated to the
use of outdated development and manufacturing technologies. The return on investment on …

A vital driving force for chemists to discover novel synthetic protocols is the improvement of
more effective synthetic technologies and sustainable methodologies. This is associated …

The study and application of contemporary optimization techniques considerably enhance
the efficiency of chemical research and manufacturing. With the dynamic progression of …

In this work, a continuous system to produce multi-hundred-gram quantities of aryl sulfonyl
chlorides is described. The scheme employs multiple continuous stirred-tank reactors …

In this study, a continuous-flow synthesis of the azo pigment Yellow 14 protocol has been
developed using a three-stream micromixing process. This method controlled the pH of the …

Electrochemistry for producing pharmaceuticals has been gaining prominence in recent
times as it offers a safer, greener, and cheaper alternative to conventional approaches for …

A strategy for combining theoretical and empirical model predictions to enhance process
monitoring and disturbance detection in continuous pharmaceutical manufacturing is …

Progress in continuous flow chemistry over the past two decades has facilitated significant
developments in the flow synthesis of a wide variety of Active Pharmaceutical Ingredients …

Accurate kinetic models for reaction systems allow for improved process understanding and
greater quality control, which is particularly beneficial as the pharmaceutical industry shifts …

1, 2-Dimethyl-3-methylsulfanylbenzene is the key intermediate of topramezone. This work
designed a two-step continuous-flow device to synthesize 1, 2-dimethyl-3 …