MicroRNAs (miRNAs) are short, noncoding RNAs that regulate gene expression by
suppressing mRNA translation and reducing mRNA stability. A miRNA can potentially bind …

Active metabolites from natural sources are the predominant molecular targets in numerous
biological studies owing to their appropriate compatibility with biological systems and …

Background Extrachromosomal circular deoxyribonucleic acid (eccDNA) is evolving as a
valuable biomarker, while little is known about its presence in urine. Methods Here, we …

Overcoming multidrug resistance (MDR) represents a major obstacle in cancer
chemotherapy. Cardiac glycosides (CGs) are efficient in the treatment of heart failure and …

Hepatocellular carcinoma (HCC) is the second leading cause of cancer related death which
needs novel drugs to improve patient outcome. Survivin overexpresses in HCC and …

The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) as multifactorial
chronic liver disease and the lack of a specific treatment have begun a new era in its …

In recent years, new therapeutic possibilities were proposed for cardiac glycosides
traditionally used to treat heart diseases, such as anticancer and antiviral activities. In this …

Introduction: MicroRNAs (miRNAs) are small, non-coding RNA molecules that epigenetically
regulate gene expression. Recently, it has been shown that miRNAs are heavily involved in …

Hepatocellular carcinoma (HCC) remains a challenge in the medical field due to its high
malignancy and mortality rates particularly for HCC, which has developed multidrug …

Cardiac glycosides (CGs) are natural compounds used to treat congestive heart failure.
They have garnered attention as a potential cancer treatment option, especially because …