Metal ion-directed functional metal–phenolic materials

H Geng, QZ Zhong, J Li, Z Lin, J Cui, F Caruso… - Chemical …, 2022 - ACS Publications
Metal ions are ubiquitous in nature and play significant roles in assembling functional
materials in fields spanning chemistry, biology, and materials science. Metal–phenolic …

Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery

Y Guo, Q Sun, FG Wu, Y Dai, X Chen - Advanced Materials, 2021 - Wiley Online Library
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …

Photo‐Reduction with NIR Light of Nucleus‐Targeting PtIV Nanoparticles for Combined Tumor‐Targeted Chemotherapy and Photodynamic Immunotherapy

D Wei, Y Huang, B Wang, L Ma… - Angewandte Chemie …, 2022 - Wiley Online Library
The development of PtIV prodrugs which are selectively reduced within cancerous cells into
their PtII therapeutically active species has received increasing attention within the last …

Mitochondrial‐targeted delivery of polyphenol‐mediated antioxidases complexes against pyroptosis and inflammatory diseases

J Zhang, B Gao, B Ye, Z Sun, Z Qian, L Yu… - Advanced …, 2023 - Wiley Online Library
Excess accumulation of mitochondrial reactive oxygen species (mtROS) is a key target for
inhibiting pyroptosis‐induced inflammation and tissue damage. However, targeted delivery …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Bioinspired Construction of a Nanozyme-Based H2O2 Homeostasis Disruptor for Intensive Chemodynamic Therapy

Y Sang, F Cao, W Li, L Zhang, Y You… - Journal of the …, 2020 - ACS Publications
The insufficient intracellular H2O2 level in tumor cells is closely associated with the limited
efficacy of chemodynamic therapy (CDT). Despite tremendous efforts, engineering CDT …

[HTML][HTML] Peroxisome inspired hybrid enzyme nanogels for chemodynamic and photodynamic therapy

X Qin, C Wu, D Niu, L Qin, X Wang, Q Wang… - Nature …, 2021 - nature.com
Peroxisome, a special cytoplasmic organelle, possesses one or more kinds of oxidases for
hydrogen peroxide (H2O2) production and catalase for H2O2 degradation, which serves as …

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

H Tian, M Zhang, G Jin, Y Jiang, Y Luan - Journal of Colloid and Interface …, 2021 - Elsevier
Chemodynamic therapy (CDT) utilizes Fenton catalysts to convert intracellular hydrogen
peroxide (H 2 O 2) into cytotoxic hydroxyl radical (OH∙) for tumor therapy, but endogenous H …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Metal–organic‐framework‐engineered enzyme‐mimetic catalysts

L Ma, F Jiang, X Fan, L Wang, C He, M Zhou… - Advanced …, 2020 - Wiley Online Library
Nanomaterial‐based enzyme‐mimetic catalysts (Enz‐Cats) have received considerable
attention because of their optimized and enhanced catalytic performances and selectivities …