Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Molecular clocks are present in almost every cell to anticipate daily recurring and
predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions …

Circadian disruptions impact nearly all people with Alzheimer's disease (AD), emphasizing
both their potential role in pathology and the critical need to investigate the therapeutic …

Physicians diagnose and administer treatment as needed; time of day is rarely considered.
Yet, accumulating evidence shows that our molecular clocks orchestrate 24-hour circadian …

Neurodegenerative diseases encompass a large group of conditions that are clinically and
pathologically diverse yet are linked by a shared pathology of misfolded proteins. The …

Background: Due to the increased life expectancy, the prevalence of aging-related health
conditions, such as cognitive impairment, dementia and Alzheimer's disease is increasing …

As the global population ages, the prevalence of neurodegenerative diseases is surging.
These disorders have a multifaceted pathogenesis, entwined with genetic and …

Intermittent fasting (IF) has demonstrated extensive health benefits through the regulation of
fatty acid metabolism and modulation of the neuroimmune microenvironment, primarily via …

Introduction Mounting evidence supports the existence of an important feedforward cycle
between sleep and neurodegeneration, wherein neurodegenerative diseases cause sleep …

Nighttime light pollution is linked to metabolic and cognitive dysfunction. Many patients with
autism spectrum disorders (ASD) show disturbances in their sleep/wake cycle, and may be …