MAIT cells and the microbiome
MF Jabeen, TSC Hinks - Frontiers in Immunology, 2023 - frontiersin.org
Mucosal associated invariant T (MAIT) cells are innate-like T lymphocytes, strikingly
enriched at mucosal surfaces and characterized by a semi-invariant αβ T cell receptor (TCR) …
enriched at mucosal surfaces and characterized by a semi-invariant αβ T cell receptor (TCR) …
The epithelial cell types and their multi-phased defenses against fungi and other pathogens
K Roe - Clinica Chimica Acta, 2024 - Elsevier
Mucus and its movements are essential to epithelial tissue immune defenses against
pathogens, including fungal pathogens, which can infect respiratory, gastrointestinal or the …
pathogens, including fungal pathogens, which can infect respiratory, gastrointestinal or the …
Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive
EW Meermeier, CL Zheng, JG Tran, S Soma… - Communications …, 2022 - nature.com
Abstract Mucosal-associated Invariant T (MAIT) cells are an innate-like T cell subset that
recognize a broad array of microbial pathogens, including respiratory pathogens. Here we …
recognize a broad array of microbial pathogens, including respiratory pathogens. Here we …
The emerging role of MAIT cell responses in viral infections
JK Sandberg, E Leeansyah, MA Eller… - The Journal of …, 2023 - journals.aai.org
Mucosal-associated invariant T (MAIT) cells are unconventional T cells with innate-like
antimicrobial responsiveness. MAIT cells are known for MR1 (MHC class I–related protein 1) …
antimicrobial responsiveness. MAIT cells are known for MR1 (MHC class I–related protein 1) …
Distinct gene expression signatures comparing latent tuberculosis infection with different routes of Bacillus Calmette-Guérin vaccination
RF Silver, M Xia, CE Storer, JR Jarvela… - Nature …, 2023 - nature.com
Tuberculosis remains an international health threat partly because of limited protection from
pulmonary tuberculosis provided by standard intradermal vaccination with Bacillus of …
pulmonary tuberculosis provided by standard intradermal vaccination with Bacillus of …
[HTML][HTML] Tim-3 expression is induced by mycobacterial antigens and identifies tissue-resident subsets of MAIT cells from patients with tuberculosis
J Jiang, Z Cao, L Xiao, B Li, S Yu, B Yang, Y Liu… - Microbes and …, 2023 - Elsevier
Tissue-resident MAIT cells in tuberculous pleural effusions, the site of tuberculosis infection,
were investigated in the study. Tim-3+ CD69+ CD103+ and CD39+ CD69+ CD103+ tissue …
were investigated in the study. Tim-3+ CD69+ CD103+ and CD39+ CD69+ CD103+ tissue …
IL-15 Superagonist N-803 Enhances IFN-γ Production of MAIT Cells in SIV+ Macaques
AL Ellis-Connell, AJ Balgeman, NM Kannal… - Infection and …, 2022 - Am Soc Microbiol
Mucosal associated invariant T (MAIT) cells are innate T cells that recognize bacterial
metabolites and secrete cytokines and cytolytic enzymes to destroy infected target cells. This …
metabolites and secrete cytokines and cytolytic enzymes to destroy infected target cells. This …
Dysfunctional bronchoalveolar effector memory CD8+ T cells in tuberculosis-exposed people living with antiretroviral-naïve HIV infection
M Mthembu, H Claassen, S Khuzwayo, V Voillet… - iScience, 2024 - cell.com
HIV causes susceptibility to respiratory pathogens, including tuberculosis (TB), but the
underlying immunological mechanisms remain incompletely understood. We obtained …
underlying immunological mechanisms remain incompletely understood. We obtained …
Mucosal‐associated invariant T cells in digestive tract: Local guardians or destroyers?
X Wang, M Liang, P Song, W Guan, X Shen - Immunology, 2023 - Wiley Online Library
Mucosa‐associated invariant T cells (MAIT) are a class of innate‐like T lymphocytes mainly
presenting CD8+ phenotype with a semi‐invariant αβ T‐cell receptor, which specifically …
presenting CD8+ phenotype with a semi‐invariant αβ T‐cell receptor, which specifically …
MAIT cell loss and reconstitution in HIV-1 disease
Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that
recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved …
recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved …