Clinical features, immunopathogenesis, and therapeutic strategies in vitiligo
Y Wang, S Li, C Li - Clinical Reviews in Allergy & Immunology, 2021 - Springer
Vitiligo is an autoimmune disease of the skin characterized by epidermal melanocyte loss
resulting in white patches, with an approximate prevalence of 0.5–2% worldwide. Several …
resulting in white patches, with an approximate prevalence of 0.5–2% worldwide. Several …
Premature cell senescence in human skin: Dual face in chronic acquired pigmentary disorders
B Bellei, M Picardo - Ageing Research Reviews, 2020 - Elsevier
Although senescence was originally described as an in vitro acquired cellular characteristic,
it was recently recognized that senescence is physiologically and pathologically involved in …
it was recently recognized that senescence is physiologically and pathologically involved in …
Melanocyte-keratinocyte cross-talk in vitiligo
AA Touni, RS Shivde, H Echuri, RTA Abdel-Aziz… - Frontiers in …, 2023 - frontiersin.org
Vitiligo is a common acquired pigmentary disorder that presents as progressive loss of
melanocytes from the skin. Epidermal melanocytes and keratinocytes are in close proximity …
melanocytes from the skin. Epidermal melanocytes and keratinocytes are in close proximity …
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo
J Huo, T Liu, F Li, X Song… - Molecular Medicine …, 2021 - spandidos-publications.com
Vitiligo (VIT) is caused by loss and degradation of functional epidermal melanocytes.
Studies have indicated that melanocyte destruction may be associated with an imbalance …
Studies have indicated that melanocyte destruction may be associated with an imbalance …
[HTML][HTML] Suppression of FADS1 induces ROS generation, cell cycle arrest, and apoptosis in melanocytes: implications for vitiligo
L Tang, J Li, W Fu, W Wu, J Xu - Aging (albany NY), 2019 - ncbi.nlm.nih.gov
Vitiligo is a potentially serious condition characterized by loss of melanin and death of
melanocytes. To identify potential therapeutic targets for vitiligo, we conducted a microarray …
melanocytes. To identify potential therapeutic targets for vitiligo, we conducted a microarray …
[HTML][HTML] The role of MicroRNAs in vitiligo: Regulators and therapeutic targets
L Li - Annals of Dermatology, 2020 - ncbi.nlm.nih.gov
Vitiligo is an acquired skin disorder clinically characterized by the progressive appearance
of white maculae due to a loss of functioning epidermal melanocytes. Studies have shown …
of white maculae due to a loss of functioning epidermal melanocytes. Studies have shown …
The immunogenetics of vitiligo: An approach toward revealing the secret of depigmentation
Vitiligo is a hypomelanotic skin disease and considered to be of autoimmune origin due to
breaching of immunological self-tolerance, resulting in inappropriate immune responses …
breaching of immunological self-tolerance, resulting in inappropriate immune responses …
Association of e-cadherin gene CDH1 polymorphism-160 C/A with susceptibility to develop vitiligo
DE Kubelis-López, NA Zapata-Salazar… - Anais Brasileiros de …, 2023 - SciELO Brasil
Vitiligo is the most frequent disorder of acquired depigmentation, characterized by achromic
patches due to the loss of melanocytes. 1, 2 Its pathogenesis is not completely understood …
patches due to the loss of melanocytes. 1, 2 Its pathogenesis is not completely understood …
Identification of candidate biomarkers and pathways associated with multiple sclerosis using bioinformatics and next generation sequencing data analysis
BM Vastrad, CM Vastrad - bioRxiv, 2023 - biorxiv.org
Multiple sclerosis (MS) is the main reason for disability caused by autoimmunity. However,
effective biomarkers for MS have not been identified. This study explored the molecular …
effective biomarkers for MS have not been identified. This study explored the molecular …
An in-depth analysis reveals two new genetic variants on 22q11. 2 associated with vitiligo in the Chinese Han population
X Tang, H Cheng, L Cheng, B Liang, M Chen… - Molecular Biology …, 2021 - Springer
Background Vitiligo is a complex disease in which patchy depigmentation is the result of an
autoimmune-induced loss of melanocytes in affected regions. On the basis of a genome …
autoimmune-induced loss of melanocytes in affected regions. On the basis of a genome …