Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues

M Foldvari, M Bagonluri - Nanomedicine: Nanotechnology, Biology and …, 2008 - Elsevier
Carbon nanotubes (CNTs) have potential novel application in nanomedicine as
biocompatible and supportive substrates, and as pharmaceutical excipients for creating …

Are carbon nanotubes a natural solution? Applications in biology and medicine

E Heister, EW Brunner, GR Dieckmann… - … applied materials & …, 2013 - ACS Publications
Carbon nanotubes and materials based on carbon nanotubes have many perceived
applications in the field of biomedicine. Several highly promising examples have been …

Biofunctionalization of carbon nanotubes/chitosan hybrids on Ti implants by atom layer deposited ZnO nanostructures

Y Zhu, X Liu, KWK Yeung, PK Chu, S Wu - Applied Surface Science, 2017 - Elsevier
Abstract One-dimensional (1D) nanostructures of ZnO using atomic layer deposition (ALD)
on chitosan (CS) modified carbon nanotubes (CNTs) were first introduced onto the surfaces …

BC nanofibres: in vitro study of genotoxicity and cell proliferation

S Moreira, NB Silva, J Almeida-Lima, HAO Rocha… - Toxicology Letters, 2009 - Elsevier
Nanomaterials have unusual properties not found in the bulk materials, which can be
exploited in numerous applications such as biosensing, electronics, scaffolds for tissue …

Multi‐functionalized carbon nano‐onions as imaging probes for cancer cells

M Frasconi, R Marotta, L Markey… - … A European Journal, 2015 - Wiley Online Library
Carbon‐based nanomaterials have attracted much interest during the last decade for
biomedical applications. Multimodal imaging probes based on carbon nano‐onions (CNOs) …

Cell-based methods for determination of efficacy for candidate therapeutics in the clinical management of cancer

JL Gordon, MA Brown, MM Reynolds - Diseases, 2018 - mdpi.com
Determination of therapeutic efficacy is a major challenge in developing treatment options
for cancer. Prior to in vivo studies, candidate therapeutics are evaluated using cell-based in …

Cytotoxicity of carboxylic acid functionalized single wall carbon nanotubes on the human intestinal cell line Caco-2

A Jos, S Pichardo, M Puerto, E Sánchez, A Grilo… - Toxicology in Vitro, 2009 - Elsevier
The unique properties of carbon nanotubes (CNTs) have been explored for their use in
biomedical sciences and in biotechnological fields; however, their possible toxic effects are …

Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells

BM Rotoli, O Bussolati, MG Bianchi, A Barilli… - Toxicology letters, 2008 - Elsevier
Little information is available upon the effects of carbon nanotubes (CNT) on the airway
barrier. Here we study the barrier function of Calu-3 human airway epithelial cells, grown on …

Analysis of the cytotoxicity of carbon-based nanoparticles, diamond and graphite, in human glioblastoma and hepatoma cell lines

KE Zakrzewska, A Samluk, M Wierzbicki, S Jaworski… - PloS one, 2015 - journals.plos.org
Nanoparticles have attracted a great deal of attention as carriers for drug delivery to cancer
cells. However, reports on their potential cytotoxicity raise questions of their safety and this …

Proteomics-based safety evaluation of multi-walled carbon nanotubes

H Haniu, Y Matsuda, K Takeuchi, YA Kim… - Toxicology and applied …, 2010 - Elsevier
This study evaluated the biological responses to multi-walled carbon nanotubes (MWCNTs).
Human monoblastic leukemia cells (U937) were exposed to As-grown MWCNTs and …