Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Background & Aims A comprehensive knowledge of the natural history of ulcerative colitis
(UC) helps understand disease evolution, identify poor prognostic markers and impact of …

In the West, the incidence and prevalence of inflammatory bowel diseases has increased in
the past 50 years, up to 8–14/100,000 and 120–200/100,000 persons, respectively, for …

Although most treatment algorithms in inflammatory bowel disease (IBD) begin with
classifying patients according to disease severity, no formal validated or consensus …

Molecular mechanisms driving disease course and response to therapy in ulcerative colitis
(UC) are not well understood. Here, we use RNAseq to define pre-treatment rectal gene …

Background Crohn's disease and ulcerative colitis are complex disorders with some shared
and many unique predisposing genes. Accurate phenotype classification is essential in …

The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

Background and Aims Inflammatory bowel diseases (IBD), encompassing Crohn's disease
(CD) and ulcerative colitis (UC), are chronic and disabling disorders. Prospective disease …

Immune-mediated diseases typically show a female preponderance. Looking at all
autoimmune diseases combined, 8 of 10 patients are females. Although not as prominent …

The goals for treatment of inflammatory bowel diseases (IBDs) are changing from
elimination of symptoms toward complete disease control—a process that demands both …