Apoptosis is a distinct mode of cell death that is responsible for deletion of cells in normal
tissues; it also occurs in specific pathologic contexts. Morphologically, it involves rapid …

▪ Abstract Apoptosis is a genetically programmed, morphologically distinct form of cell death
that can be triggered by a variety of physiological and pathological stimuli. Studies …

Interleukin 1β-converting enzyme-like proteases (caspases) are crucial components of cell
death pathways. Among the caspases identified, caspase-3 stands out because it is …

The concept of apoptotic cell death as an essential part of the development and life of
complex organisms has been devised in different situations and tested from various angles …

Various molecules such as cytokines and anticancer drugs, as well as factor deprivation,
rapidly induce apoptosis (programmed cell death),, which is morphologically characterized …

We have generated H-2b mice with a homozygoua null mutation in the granzyme (gzm) B
gene. Gzm B is a neutral serine protease with Aspase activity that is found only in …

THE recent generation of perform knock-out mice1, 2 has demonstrated a crucial role for the
pore-forming perforin in cytolytic T-lymphocyte (CTL)-mediated cytolysis. Perforin-deficient …

Background: Avirulent pathogens elicit a battery of plant defenses, often accompanied by
collapse of the challenged cells. In soybean cells, sustained accumulation of H 2 O 2 from …

To date, apoptosis has been characterized biochemically by the production of 180–200 bp
internucleosomal DNA fragments resulting from the activation of an endonuclease (s). The …

Programmed cell death is often triggered by the interaction of some cytokines with their cell
surface receptors. Here, we report that gamma interferon (IFN-gamma) induced in HeLa …