Inverse modeling approaches in cardiovascular medicine are a collection of methodologies
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …

Background—The objective of this study is to assess the dynamic alterations of myocardial
microstructure and strain between diastole and systole in patients with dilated …

Biomechanical modeling has a wide range of applications in the medical field, including in
diagnosis, treatment planning and tissue engineering. The key to these predictive models …

Cardiac digital twins provide a physics and physiology informed framework to deliver
personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to …

Computational biomechanics plays an important role in biomedical engineering: using
modeling to understand pathophysiology, treatment and device design. While experimental …

In the past years, a number of cardiac electromechanics models have been developed to
better understand the excitation–contraction behavior of the heart. However, there is no …

Parameterised patient-specific models of the heart enable quantitative analysis of cardiac
function as well as estimation of regional stress and intrinsic tissue stiffness. However, the …

Patient specific models of ventricular mechanics require the optimization of their many
parameters under the uncertainties associated with imaging of cardiac function. We present …

The determinant role of the annulus fibrosus interlamellar zones in the intervertebral disc
transversal and volumetric responses and hence on their corresponding three-dimensional …

In this work, a fully three-dimensional model of the human intervertebral disc is proposed
within a purely analytical framework in the final goal to create time and cost-efficient patient …