Interpreting crosstalk between TNF-α and NGF: potential implications for disease

Y Takei, R Laskey - Trends in Molecular Medicine, 2008 - cell.com
Tumour necrosis factor-α (TNF-α) is a proinflammatory cytokine, whereas nerve growth
factor (NGF) is a neurotrophin that can promote neural cell survival, differentiation and …

Local immunotherapy with rhTNF-α mutein induces strong antitumor activity without overt toxicity—a review

SJ Terlikowski - Toxicology, 2002 - Elsevier
Tumor necrosis factor (TNF-α) is a cytokine possessing antitumor and immunomodulatory
properties. The studies reviewed in the present paper evaluate the effect of intratumor or …

Occlusion of pulmonary vessels by megakaryocytes after treatment with tumour necrosis factor-alpha (TNF-α)

S Sulkowski, S Terlikowski, M Sulkowska - Journal of comparative …, 1999 - Elsevier
Pulmonary thrombosis in the course of shock remains life-threatening, despite advances in
diagnosis, prophylaxis and therapy of the disease. Tumour necrosis factor-alpha (TNF-α) is …

Lack of association between the Met196Arg polymorphism in the TNFR2 gene and autoimmune diseases accompanied by vasculitis including SLE in Japanese

M Takahashi, H Hashimoto, M Akizuki… - Tissue …, 2001 - Wiley Online Library
A polymorphism in high‐affinity receptor of TNF (TNFR2) gene, Met196Arg, was reported to
be associated with systemic lupus erythematosus (SLE) in Japanese, whereas the …

Role of TNF-α in human female reproduction

J Calleja-Agius, S Muttukrishna… - Expert review of …, 2009 - Taylor & Francis
TNF-α is a highly versatile cytokine, playing an important role in both apoptosis and
inflammation, which is central to reproduction. It belongs to the Th1 type of cytokines. Thus …

The biallelic variable number of tandem repeats of the tumor necrosis factor receptor 2 promoter in systemic lupus erythematosus

Y Lee, Y Rho, S Choi, J Ji, G Song - Rheumatology international, 2003 - Springer
The objective of this study was to investigate whether the variable number of tandem repeats
(VNTR) of the tumor necrosis factor receptor 2 (TNFR2) promoter is associated with …

The influence of recombinant human tumor necrosis factor α and its muteins used alone or in combination with 2-chlorodeoxyadenosine on normal and leukemic …

A Korycka, T Robak - Leukemia research, 1997 - Elsevier
We investigated the influence of TNFα and its muteins III, V and VI on the colony growth of
normal and CML CFU-GM cells as well as on CFU-L clonogenic blasts from AMI patients in …

Listeria monocytogenes infection in mice treated with pentoxifylline

M Brzychcy, M Klink, H Tchórzewski… - Zentralblatt für …, 1997 - Elsevier
The course of L. monocytogenes infection was followed in mice treated with pentoxifyl-line
(POF), a known inhibitor of endogenous tumor necrosis factor (TNF) formation …

The antitumor effect of intraperitoneal treatment with rhTNF-α muteins on Ehrlich ascites tumor growth

S Terlikowski, HF Nowak - Cancer biotherapy & …, 2000 - liebertpub.com
The intraperitoneal (ip) treatment with recombinant human tumor necrosis factor-α (rhTNF-α)
is one of the possible therapies for tumors that are confined to the abdominal cavity. Clinical …

A comparison of the Antileukaemic Effects of Recombinant Human Tumour Necrosis Factor‐α and its Muteins on Leukaemia L1210 and Leukaemia P388 in Mice

K Warzocha, J Góra-Tybor, M Kwinkowski… - Mediators of …, 1994 - Wiley Online Library
We investigated the influence of recombinant human tumour necrosis factor alpha (TNF‐α)
and its derivatives termed muteins III, V, VI—in which the first 3 to 7 amino acids of native …