Following myocardial infarction (MI), circulating blood monocytes respond to chemotactic
factors, migrate into the infarcted myocardium, and differentiate into macrophages. At the …

Cytotoxicity and Wound Healing Evidence for the Role of Elastase in ARDS in Humans
Animal Models of Lung Injury and Leukocyte Elastase Studies of Protease Inhibitors and …

Background We previously reported the prevalence and associations of abdominal aortic
aneurysm (AAA) in 73,451 veterans aged 50 to 79 years who underwent ultrasound …

Macrophages are either classically (M1) or alternatively-activated (M2). Whereas this
nomenclature was generated from monocyte-derived macrophages treated in vitro with …

Marfan syndrome is associated with early death due to aortic aneurysm. The condition is
caused by mutations in the gene (FBN1) encoding fibrillin-1, a major constituent of …

Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

Macrophages accumulate in ischemic areas of such pathological tissues as solid tumors,
atherosclerotic plaques and arthritic joints. Studies have suggested that hypoxia alters the …

[Frontiers in Bioscience 11, 479-491, January 1, 2006] 479 Matrix metalloproteinases: roles in
cancer and metastasis Barbara Fin Page 1 [Frontiers in Bioscience 11, 479-491, January 1 …

IL-13 potently stimulates eosinophilic and lymphocytic inflammation and alveolar
remodeling in the lung, effects that depend on the induction of various matrix …

Objective: Aortic aneurysm has traditionally been considered a manifestation of
atherosclerosis, but recent evidence suggests an independent pathogenesis, possibly …