Allogeneic blood or bone-marrow transplantation (alloBMT) is a potentially curative
treatment for a variety of haematological malignancies and nonmalignant diseases …

There is a strong graft-versus-leukemia (GVL) effect of allogeneic stem cell transplantation
(SCT) due to elimination of tumor cells by alloimmune effector lymphocytes. When leukemia …

PURPOSE Patients with relapsed or refractory T-cell acute lymphoblastic leukemia (r/r T-
ALL) have few options and poor prognosis. The aim was to assess donor-derived anti-CD7 …

We evaluated the safety and efficacy of high-dose, posttransplantation cyclophosphamide
(Cy) to prevent graft rejection and graft-versus-host disease (GVHD) after outpatient …

Toxicities have limited the use of allogeneic hematopoietic cell transplantation (HCT) to
younger, medically fit patients. In a canine HCT model, a combination of postgrafting …

Cyclophosphamide (Cy) is a potent immunosuppressive agent that is selectively toxic to
lymphocytes proliferating in response to recent antigen stimulation. In animal models, both …

Because information on management and outcome of AML relapse after allogeneic
hematopoietic stem cell transplantation (HSCT) with reduced intensity conditioning (RIC) is …

Background Since allogeneic stem-cell transplantation can induce curative graft-versus-
leukemia reactions in patients with hematologic cancers, we sought to induce analogous …

Abstract Treatment of leukemia by myeloablative conditioning and transplantation of major
histocompatibility complex (MHC)–mismatched stem cells is generally avoided because of …

A sequential regimen of chemotherapy, reduced-intensity conditioning (RIC) for allogeneic
stem cell transplantation (SCT), and prophylactic donor lymphocyte transfusion (pDLT) was …