The use of animals as models to address fundamental questions on the molecular basis of
cancer and for preclinical study of cancer therapeutics has a long history, and important …

Expression of Ki‐67, a nuclear antigen protein present in all cycling cells, is used to
determine the growth fraction of tumors. The aim of this study was to evaluate the role and …

Local macrophage proliferation in human glomerulonephritis. Background Local
macrophage proliferation has been described in several animal models of …

A 70-year-old male presented with a plasma cell granuloma extending from the extracranial
to the in tracranial space. Findings of preoperative magnetic resonance imaging and …

OBJECTIVE: The prognostic significance of quantitative measurement of tumor proliferative
activity was evaluated for oligodendroglial tumors. METHODS: Ki-67/MIB-1 …

Molecular tumor markers are often studied in colorectal cancer using immunohistochemistry
to determine their prognostic or predictive value. Protein expression is typically assigned a …

Local macrophage proliferation in the progression of glomerular and tubulointerstitial injury
in rat anti-GBM glomerulonephritis. The aim of this study was to examine the contribution of …

The monoclonal antibody MIB1 recognizing the Ki‐67 antigen in formalin‐fixed, paraffin‐
embedded tissue was used to study the proliferative activity in 44 adenoid cystic carcinomas …

Tubules are the major site of M-CSF production in experimental kidney disease: Correlation
with local macrophage proliferation. Background Local proliferation of macrophages occurs …

Object The intrinsic radioresistance of certain cancer cells may be closely associated with
the constitutive activation of nuclear factor–kappa B (NF-κB) activity, which may lead to …