Etiologies of sperm DNA damage and its impact on male infertility
MK Panner Selvam, RF Ambar, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is
considered the cornerstone of laboratory evaluation of male infertility, but it has its own …
considered the cornerstone of laboratory evaluation of male infertility, but it has its own …
Investigating ROS sources in male infertility: a common end for numerous pathways
G Lavranos, M Balla, A Tzortzopoulou, V Syriou… - Reproductive …, 2012 - Elsevier
Reactive oxygen species (ROS) are active byproducts of aerobic metabolism. Although they
are constantly produced during normal cellular activities in the mitochondria, their action is …
are constantly produced during normal cellular activities in the mitochondria, their action is …
[HTML][HTML] Increasing scientific confidence in adverse outcome pathways: application of tailored Bradford-Hill considerations for evaluating weight of evidence
Systematic consideration of scientific support is a critical element in developing and,
ultimately, using adverse outcome pathways (AOPs) for various regulatory applications …
ultimately, using adverse outcome pathways (AOPs) for various regulatory applications …
Bisphenol A induces reactive oxygen species generation in the liver of male rats
Bisphenol A, an environmental contaminant, widely used as a monomer in polycarbonate
plastics, has been shown to cause abnormalities in liver of rats and mice. The nature and …
plastics, has been shown to cause abnormalities in liver of rats and mice. The nature and …
Induction of oxidative stress by bisphenol A in the epididymal sperm of rats
Bisphenol A has been shown to affect the reproduction of male rats and mice. However, the
mechanism of action of bisphenol A on the epididymal sperm is not elucidated. The present …
mechanism of action of bisphenol A on the epididymal sperm is not elucidated. The present …
Insecticide imidacloprid induces morphological and DNA damage through oxidative toxicity on the reproductive organs of developing male rats
We investigated whether treatment with imidacloprid would induce morphological changes,
DNA fragmentation, antioxidant imbalance and apoptosis in the reproductive system of …
DNA fragmentation, antioxidant imbalance and apoptosis in the reproductive system of …
Assessment of imidacloprid toxicity on reproductive organ system of adult male rats
In the current study it was aimed to investigate the toxicity of low doses of imidacloprid (IMI)
on the reproductive organ systems of adult male rats. The treatment groups received 0.5 (IMI …
on the reproductive organ systems of adult male rats. The treatment groups received 0.5 (IMI …
Effect of nonylphenol on the antioxidant system in epididymal sperm of rats
Nonylphenol, an environmental contaminant, has been shown to induce reproductive
abnormalities in male rats. The nature and mechanism of action of nonylphenol on the …
abnormalities in male rats. The nature and mechanism of action of nonylphenol on the …
[HTML][HTML] Experimental evidence of 2, 3, 7, 8-tetrachlordibenzo-p-dioxin (TCDD) transgenerational effects on reproductive health
L Gaspari, F Paris, N Kalfa, MO Soyer-Gobillard… - International Journal of …, 2021 - mdpi.com
Previous studies have demonstrated that endocrine disruptors (EDs) can promote the
transgenerational inheritance of disease susceptibility. Among the many existing EDs, 2, 3 …
transgenerational inheritance of disease susceptibility. Among the many existing EDs, 2, 3 …
Protective effect of N-acetylcysteine on bisphenol A-induced cognitive dysfunction and oxidative stress in rats
S Jain, CHM Kumar, UD Suranagi… - Food and chemical …, 2011 - Elsevier
Bisphenol A (BPA) is commonly used as a monomer in polycarbonate plastics. The present
study was designed to investigate the effect of BPA on cognitive functions and oxidative …
study was designed to investigate the effect of BPA on cognitive functions and oxidative …