Mechanisms involved in the aging-induced vascular dysfunction

M El Assar, J Angulo, S Vallejo, C Peiró… - Frontiers in …, 2012 - frontiersin.org
Vascular aging is a key process determining health status of aged population. Aging is an
independent cardiovascular risk factor associated to an impairment of endothelial function …

Endothelialization mechanisms in vascular grafts

PF Sánchez, EM Brey… - Journal of tissue …, 2018 - Wiley Online Library
Despite the wide variety of tissue‐engineered vascular grafts that are currently being
developed, autologous vessels, such as the saphenous vein, are still the gold standard …

Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus

JM Kahlenberg, SG Thacker, CC Berthier… - The Journal of …, 2011 - journals.aai.org
Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous
manifestations including severe organ damage and vascular dysfunction leading to …

An integrated platform for isolation, processing, and mass spectrometry-based proteomic profiling of rare cells in whole blood*[s]

S Li, BD Plouffe, AM Belov, S Ray, X Wang… - Molecular & Cellular …, 2015 - ASBMB
Isolation and molecular characterization of rare cells (eg circulating tumor and stem cells)
within biological fluids and tissues has significant potential in clinical diagnostics and …

Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E …

N Ervinna, T Mita, E Yasunari, K Azuma… - …, 2013 - academic.oup.com
Abstract Dipeptyl peptidase-4 (DPP-4) inhibitors modulate the progression of
atherosclerosis. To gain insights into their mechanism of action, 9-wk-old male …

Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice

B Meng, Y Li, Y Ding, X Xu, L Wang, B Guo, B Zhu… - Science …, 2021 - science.org
Whether bone marrow modulates systemic metabolism remains unknown. Here, we found
that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated …

Effects and mechanisms of Taohong Siwu decoction on the prevention and treatment of myocardial injury

CL Shao, GH Cui, HD Guo - Frontiers in pharmacology, 2022 - frontiersin.org
Taohong Siwu decoction (THSWD) is one of the classic prescriptions for promoting blood
circulation and removing blood stasis. With the continuous in-depth excavation in basic and …

An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage

JM Kahlenberg, S Yalavarthi, W Zhao… - Arthritis & …, 2014 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome
associated with organ damage and an elevated risk of cardiovascular disease resulting from …

Role and implications of the CXCL12/CXCR4/CXCR7 axis in atherosclerosis: still a debate

HAS Murad, MM Rafeeq, TMA Alqurashi - Annals of medicine, 2021 - Taylor & Francis
Atherosclerosis is one of the leading causes of mortality and morbidity worldwide.
Chemokines and their receptors are implicated in the pathogenesis of atherosclerosis …

Circulating endothelial progenitor cells as biomarkers for prediction of cardiovascular outcomes

C Bakogiannis, D Tousoulis… - Current medicinal …, 2012 - ingentaconnect.com
Experimental studies suggest that bone marrow-derived endothelial progenitor cells (EPCs)
play an important role in the maintenance of endothelial integrity and hemostasis. The …