This Review compiles the evolution, mechanistic understanding, and more recent advances
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …

Whereas numerous asymmetric methods for formation of quaternary carbon stereocenters in
cyclic systems have been documented, the construction of acyclic quaternary carbon …

The asymmetric construction of all-carbon quaternary centres within acyclic settings
represents a long-standing challenge for synthetic chemists. Alongside polar and radical …

The asymmetric alkylation of enolates is a particularly versatile method for the construction
of α-stereogenic carbonyl motifs, which are ubiquitous in synthetic chemistry. Over the past …

Over the past 20 years, the asymmetric synthesis of acyclic tetrasubstituted stereocenters by
Pd-catalyzed asymmetric allylic alkylation (Pd-AAA) strategies has seen considerable …

Creating a perfect catalyst to operate enzyme-like chiral recognition has been a long-sought
aim. A challenging example in this context is constructing acyclic all-carbon quaternary …

Asymmetric reactions that convert racemic mixtures into enantioenriched amines are of
significant importance due to the prevalence of amines in pharmaceuticals, with about 60 …

Chiral acyclic all-carbon quaternary stereocenters are widely present in natural products
and pharmaceuticals. However, their introduction remains a challenging topic in the …

Enantioselective construction of all-carbon quaternary stereocenters has attracted much
attention over the past few decades. A variety of catalytic asymmetric methods have been …

In the presence of boron trifluoride, conjugate addition of organocuprates to α-substituted α,
β-unsaturated N-tert-butanesulfinyl ketimines provides facile access to acyclic β, β …