Panel 4: Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

RL Marsh, C Aho, J Beissbarth, S Bialasiewicz… - International journal of …, 2020 - Elsevier
Objective To perform a comprehensive review of otitis media microbiome literature
published between 1 st July 2015 and 30th June 2019. Data sources PubMed database …

Non‐coding RNA and cholesteatoma

I Jovanovic, M Zivkovic, S Jesic… - Laryngoscope …, 2022 - Wiley Online Library
Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which
pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends …

Chronic inflammation of middle ear cholesteatoma promotes its recurrence via a paracrine mechanism

M Schürmann, F Oppel, S Shao… - Cell Communication and …, 2021 - Springer
Background Cholesteatoma disease is an expanding lesion in the middle ear. Hearing loss
and facial paralysis alongside with other intracranial complications are found. No …

Whole exome sequencing study identifies candidate loss of function variants and locus heterogeneity in familial cholesteatoma

R Cardenas, P Prinsley, C Philpott, MF Bhutta… - Plos one, 2023 - journals.plos.org
Cholesteatoma is a rare progressive disease of the middle ear. Most cases are sporadic, but
some patients report a positive family history. Identifying functionally important gene variants …

Identification of novel genes and biological pathways that overlap in infectious and nonallergic diseases of the upper and lower airways using network analyses

EE Baschal, ED Larson, TC Bootpetch Roberts… - Frontiers in …, 2020 - frontiersin.org
Previous genetic studies on susceptibility to otitis media and airway infections have focused
on immune pathways acting within the local mucosal epithelium, and outside of allergic …

[HTML][HTML] Generation of DNA-aptamers targeting galectin-7 for the identification of cholesteatoma residue

S Liu, E Takemasa, Y Suzuki, A Javkhlant… - Journal of …, 2022 - Elsevier
Purpose Aiming at complete excision of cholesteatoma during trympanomastoidectomy and
therefore reducing the risk of recurrence, intraoperative imaging techniques are required to …

Предикторы рецидивирующей патологии и прогноз результатов хирургического лечения пациентов с приобретенной холестеатомой среднего уха

ИА Аникин, ТА Бокучава, НН Хамгушкеева… - Вестник …, 2020 - elibrary.ru
Проведен ретроспективный анализ итогов хирургического лечения 436 пациентов (332
взрослых и 104 детей в возрасте до 15 лет) с приобретенной холестеатомой среднего …