Relapsed medulloblastoma in pre-irradiated patients: current practice for diagnostics and treatment

RM Hill, SLA Plasschaert, B Timmermann, C Dufour… - Cancers, 2021 - mdpi.com
Simple Summary Medulloblastoma is the commonest malignant brain tumour of childhood.
Disease relapse following maximal multi-modal therapy including upfront craniospinal …

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

J DeSisto, JT Lucas Jr, K Xu, A Donson, T Lin… - Nature …, 2021 - nature.com
Radiation-induced high-grade gliomas (RIGs) are an incurable late complication of cranial
radiation therapy. We performed DNA methylation profiling, RNA-seq, and DNA sequencing …

Defining the molecular features of radiation-induced glioma: a systematic review and meta-analysis

JP Whitehouse, M Howlett, A Federico… - Neuro-Oncology …, 2021 - academic.oup.com
Background Cranial radiation therapy is essential in treating many pediatric cancers,
especially brain tumors; however, its use comes with the risk of developing second …

The role of diffusion tensor imaging metrics in the discrimination between cerebellar medulloblastoma and brainstem glioma

NM Duc - Pediatric blood & cancer, 2020 - Wiley Online Library
Background Differentiation between cerebellar medulloblastoma and brainstem glioma is
necessary for certain clinical circumstances. We aimed to evaluate the function of diffusion …

The role of apparent diffusion coefficient in the differentiation between cerebellar medulloblastoma and brainstem glioma

P Minh Thong, N Minh Duc - Neurology International, 2020 - mdpi.com
For certain clinical circumstances, the differentiation between cerebellar medulloblastoma
and brainstem glioma is essential. We aimed to evaluate the role played by the apparent …

[HTML][HTML] Mesenchymal epithelial transition factor signaling in pediatric nervous system tumors: implications for malignancy and cancer stem cell enrichment

AR Khater, T Abou-Antoun - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Malignant nervous system cancers in children are the most devastating and worrisome
diseases, specifically due to their aggressive nature and, in some cases, inoperable location …

Surgery for recurrent medulloblastoma: a review

A Rolland, K Aquilina - Neurochirurgie, 2021 - Elsevier
Introduction Medulloblastoma (MB) is the most common malignant brain tumour in children.
Despite significant progress in its management, a proportion of children relapse; tumour …

A novel orthotopic patient-derived xenograft model of radiation-induced glioma following medulloblastoma

JP Whitehouse, M Howlett, H Hii, C Mayoh, M Wong… - Cancers, 2020 - mdpi.com
Simple Summary Radiation-induced glioma (RIG) is a highly aggressive brain cancer
arising as a consequence of radiation therapy, for which there is currently no effective …

The effectiveness of diffusion kurtosis imaging metrics for distinguishing between brainstem glioma and cerebellar medulloblastoma

NM Duc - La Clinica Terapeutica, 2024 - clinicaterapeutica.it
BACKGROUND: In some clinical situations, distinguishing between cerebellar
medulloblastoma and brainstem glioma is important. We assessed whether diffusion …

[PDF][PDF] Возможности персонификации терапии рефрактерных и рецидивирующих форм медуллобластомы у детей: обзор литературы

ЮВ Диникина, ОГ Желудкова… - Современная …, 2023 - omnidoctor.ru
Аннотация Медуллобластома (МБ) является наиболее частой злокачественной
опухолью центральной нервной системы у детей. Несмотря на использование …