Trends in the development of miRNA bioinformatics tools
L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …
recognition of cognate sequences and interference of transcriptional, translational or …
A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
mirDIP 4.1—integrative database of human microRNA target predictions
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
miRNet-dissecting miRNA-target interactions and functional associations through network-based visual analysis
Y Fan, K Siklenka, SK Arora, P Ribeiro… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) can regulate nearly all biological processes and their dysregulation is
implicated in various complex diseases and pathological conditions. Recent years have …
implicated in various complex diseases and pathological conditions. Recent years have …
The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations
Y Ru, KJ Kechris, B Tabakoff, P Hoffman… - Nucleic acids …, 2014 - academic.oup.com
Abstract microRNAs (miRNAs) regulate expression by promoting degradation or repressing
translation of target transcripts. miRNA target sites have been catalogued in databases …
translation of target transcripts. miRNA target sites have been catalogued in databases …
Mesenchymal stromal cell-derived extracellular vesicles attenuate dendritic cell maturation and function
Mesenchymal stromal cells (MSCs) are potent regulators of immune responses largely
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are …
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are …
miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database
Since the initial release of miRPathDB, tremendous progress has been made in the field of
microRNA (miRNA) research. New miRNA reference databases have emerged, a vast …
microRNA (miRNA) research. New miRNA reference databases have emerged, a vast …
MirGeneDB 2.0: the metazoan microRNA complement
Small non-coding RNAs have gained substantial attention due to their roles in animal
development and human disorders. Among them, microRNAs are special because …
development and human disorders. Among them, microRNAs are special because …
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS
A Varcianna, MA Myszczynska, LM Castelli, B O'Neill… - …, 2019 - thelancet.com
Background Astrocytes regulate neuronal function, synaptic formation and maintenance
partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) …
partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) …
Extracellular vesicles secreted by atherogenic macrophages transfer microRNA to inhibit cell migration
MA Nguyen, D Karunakaran, M Geoffrion… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—During inflammation, macrophages secrete vesicles carrying RNA, protein, and
lipids as a form of extracellular communication. In the vessel wall, extracellular vesicles …
lipids as a form of extracellular communication. In the vessel wall, extracellular vesicles …