Recent advances in the genetics of idiopathic pulmonary fibr... : Current Opinion in Pulmonary
Medicine Recent advances in the genetics of idiopathic pulmonary fibrosis : Current Opinion …

Recent genetic and genomic advancements have elucidated the complex etiology of
idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases …

Background In familial pulmonary fibrosis (FPF) at least two biological relatives are affected.
Patients with FPF have diverse clinical features. Research question We aimed to …

Background Several rare surfactant-related gene (SRG) variants associated with interstitial
lung disease are suspected to be associated with lung cancer, but data are missing. We …

Background Gene variants have been identified in patients with familial or sporadic
idiopathic pulmonary fibrosis (IPF). These variants may partially account for the genetic risk …

With increasing awareness of genetic factors and variants involved in the pathogenesis of
interstitial lung diseases (ILDs) and expanded availability of genetic testing, pulmonologists …

The human lung is structurally complex, with a diversity of specialized epithelial, stromal and
immune cells playing specific functional roles in anatomically distinct locations, and large …

Pulmonary fibrosis is frequently divided into “familial”, ie where two or more related family
members are affected by a fibrotic interstitial lung disease, or “sporadic”, where there is no …

Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that can develop in
patients with connective tissue diseases (CTD). Establishing autoimmunity in ILD impacts …

Background Pulmonary fibrosis (PF) is a shared characteristic of chronic interstitial lung
diseases of mixed aetiology. Previous studies on PF highlight a pathogenic role for common …