Novel applications of NSAIDs: Insight and future perspectives in cardiovascular, neurodegenerative, diabetes and cancer disease therapy

E Kaduševičius - International Journal of Molecular Sciences, 2021 - mdpi.com
Once it became clear that inflammation takes place in the modulation of different
degenerative disease including neurodegenerative, cardiovascular, diabetes and cancer …

Repurposing some of the Well-known Non-steroid Anti-inflammatory Drugs (NSAIDs) for Cancer Treatment

SM Sousa, CPR Xavier… - Current Topics in …, 2023 - ingentaconnect.com
Drug repurposing is a strategy used to develop new treatments based on approved or
investigational drugs outside the scope of their original clinical indication. Since this …

Designing coordination polymers as multi-drug-self-delivery systems for tuberculosis and cancer therapy: in vitro viability and in vivo toxicity assessment

P Biswas, HK Datta, P Dastidar - Biomaterials Science, 2022 - pubs.rsc.org
A proof of concept for designing multi-drug-delivery systems suitable for self-drug-delivery is
disclosed. Simple coordination chemistry was employed to anchor two kinds of drugs …

The association between circulating docosahexaenoic acid and lung cancer: A Mendelian randomization study

H Zhao, S Wu, Z Luo, H Liu, J Sun, X Jin - Clinical Nutrition, 2022 - Elsevier
Background Lung cancer is a malignant tumor with a high incidence, it is vital to identify
modifiable and avoidable risk factors for primary prevention, which can significantly lower …

Electroanalysis of 4′-hydroxydiclofenac for CYP2C9 enzymatic assay

AV Kuzikov, TA Filippova, RA Masamrekh… - Electrocatalysis, 2022 - Springer
In this work, we have investigated the electrochemical properties of 4′-hydroxydiclofenac,
which is the main product of cytochrome P450 2C9 (CYP2C9)-dependent metabolism of a …

Combinatorial effect of diclofenac with piperine and D-limonene on inducing apoptosis and cell cycle arrest of breast cancer cells

S Sankar, GK Muthukaliannan - Asian Pacific Journal of Tropical …, 2023 - journals.lww.com
Objective: To investigate the potential synergistic activity of diclofenac with piperine and D-
limonene in inducing apoptosis and cell cycle arrest in breast cancer MCF-7 cells. Methods …

N-trans-p-coumaroyltyramine enhances indomethacin-and diclofenac-induced apoptosis through endoplasmic reticulum stress-dependent mechanism in MCF-7 cells

A Wongsakul, N Lertnitikul, R Suttisri… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: The anticancer potential of indomethacin and diclofenac has been
reported against several types of cancer cells. In this study, we investigated the …

Internship Report and Monograph" NSAIDS-loaded nanocarriers for next generation cancer treatment"

CR Mesquita - 2023 - search.proquest.com
Amidst the use of a variety of cancer treatment strategies in the clinical setting (eg, surgery,
chemotherapy, irradiation, and immunotherapy), cancer-related mortality remains one of the …

DICLOFENAC: A Review on Its Synthesis, Mechanism of Action, Pharmacokinetics, Prospect and Environmental Impact

HA Satar, E Yousif, A Ahmed - Al-Mustaqbal Journal of …, 2024 - mjpms.uomus.edu.iq
Diclofenac, potent a nonsteroidal anti-inflammatory drug, used in the treatment of
inflammation, pain and fever associated with a wide range of disease condition. This review …