The biomanufacturing industry has now the opportunity to upgrade its production processes
to be in harmony with the latest industrial revolution. Technology creates capabilities that …

The ability to measure all process variables is of great importance in the field of bioprocess
monitoring and control, and continuous, real‐time measurements are highly desired. The …

The FDA's process analytical technology initiative encourages drug manufacturers to apply
innovative ideas to better understand their processes. There are many challenges to …

The use of spectroscopic sensors for bioprocess monitoring is a powerful tool within the
process analytical technology (PAT) initiative of the US Food and Drug Administration …

During the last years, the use of biosensors in food analysis has gained considerable
interest. These analytical devices provide highly selective, sensitive and cost-effective …

Stem cells have emerged as the starting material of choice for bioprocesses to produce cells
and tissues to treat degenerative, genetic, and immunological disease. Translating the …

The best method for process control is the use of model‐based solutions, based on process
analytical technology for online monitoring of critical process variables, product quality …

Mitigating risks to biotherapeutic protein production processes and products has driven the
development of targeted process analytical technology (PAT); however implementing PAT …

In this study, the application of Raman spectroscopy to the simultaneous quantitative
determination of glucose, glutamine, lactate, ammonia, glutamate, total cell density (TCD) …

Cell culture encompasses procedures for extracting cells from their natural tissue and
cultivating them under controlled artificial conditions. During this process, various factors …