[PDF][PDF] 甘草酸药理作用的研究进展

韩瑶聃, 王彬, 王政雨, 张亚弢, 杨凌云, 周金培… - 中国新药 …, 2012 - researchgate.net
甘草的使用已有几千年历史, 现在在世界各地广泛应用. 甘草酸是中药甘草根部提取物中的重要
成分之一, 含有2 分子葡萄糖醛酸和1 分子甘草次酸, 具有水溶性. 甘草酸在临床上得到了广泛 …

Challenges in developing medicinal plant databases for sharing ethnopharmacological knowledge

SS Ningthoujam, AD Talukdar, KS Potsangbam… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Major research contributions in
ethnopharmacology have generated vast amount of data associated with medicinal plants …

Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico …

R Arunkumar, G Sharmila, P Elumalai, K Senthilkumar… - Phytomedicine, 2012 - Elsevier
PURPOSE: Diallyl Disulfide (DADS) is one of the major components of garlic, which inhibits
the proliferation of various cancer cells. Our previous studies showed that DADS inhibits cell …

Berberis lyceum and Fumaria indica: in vitro cytotoxicity, antioxidant activity, and in silico screening of their selected phytochemicals as novel hepatitis C virus …

K Brice Landry, S Tariq, A Malik, M Sufyan… - Journal of …, 2022 - Taylor & Francis
Berberis lyceum and Fumaria indica are two Pakistani indigenous herbal medicines used to
treat liver infections, including hepatitis C virus (HCV). This study aimed to evaluate the …

Pharmacoinformatics approach for investigation of alternative potential hepatitis C virus nonstructural protein 5B inhibitors

MU Mirza, NUH Ghori, N Ikram, AR Adil… - Drug design …, 2015 - Taylor & Francis
Hepatitis C virus (HCV) is one of the major viruses affecting the world today. It is a highly
variable virus, having a rapid reproduction and evolution rate. The variability of genomes is …

Protective effects of hepatocyte-specific glycyrrhetic derivatives against carbon tetrachloride-induced liver damage in mice

Y Yang, L Yang, Y Han, Z Wu, P Chen, H Zhang… - Bioorganic …, 2017 - Elsevier
Glycyrrhetic acid (GA), the main hydrolysate of glycyrrhizic acid extracted from the roots of
the Chinese herb Glycyrrhiza glabra, was reported to be accumulated in hepatocytes due to …

[PDF][PDF] In silico docking studies on the anti-cancer effect of thymoquinone on interaction with phosphatase and tensin homolog located on chromosome 10q23: A …

G Nithya, D Sakthisekaran - Asian J. Pharm. Clin. Res, 2015 - Citeseer
Objective: The statistics on cancer imposes the urge to extend new methods to control this
deadly form of the disease. Phosphatase and tensin homolog located on chromosome …

Targeting the ENV spike protein of HIV with naturally occurring compounds: an in-silico study for drug designing

S Sreeram, R Sathishkumar, PS Amritha - Advances in Traditional …, 2023 - Springer
Abstract Human Immunodeficiency Virus (HIV) infects human by destroying the immune
system. The types of HIV strains HIV-1 and HIV-2, among HIV-1 being more prevalent and …

[PDF][PDF] Exploring the polymerase activity of chikungunya viral non structural protein 4 (nsP4) using molecular modeling, epharmacophore and docking studies.

SP Kumar, RG Kapopara, MI Patni… - International Journal of …, 2012 - academia.edu
Chikungunya viral RNA-dependent RNA polymerase (RdRp) activity is conferred by non
structural protein 4 (nsp4), an important protein target towards the development of antiviral …

[PDF][PDF] Molecular Docking and Pharmacophore-Based Virtual Screening of Novel Inhibitors for HCV NS5B RNA-Dependent RNA Polymerase Enzyme from Crude …

LAJ Shittu, AM Jinadu, RK Shittu, SA Shittu - Am. J. Biotech. Bioinfo, 2018 - academia.edu
Primarily the crackdown of the entire human genome about a few decades ago has
positively impacted on the enhanced roles of computational tools applications in modern …