Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Electroorganic synthesis under flow conditions

M Elsherbini, T Wirth - Accounts of chemical research, 2019 - ACS Publications
Conspectus Despite the long history of electroorganic synthesis, it did not participate in the
mainstream of chemical research for a long time. This is probably due to the lack of …

A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

RS Keri, MR Patil, SA Patil, S Budagumpi - European Journal of Medicinal …, 2015 - Elsevier
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

1, 2, 3-Triazoles of 8-hydroxyquinoline and HBT: Synthesis and studies (DNA binding, antimicrobial, molecular docking, ADME, and DFT)

N Nehra, RK Tittal, VD Ghule - ACS omega, 2021 - ACS Publications
A new series of 1, 2, 3-triazole hybrids containing either 2-or 4-hydroxyphenyl benzothiazole
(2-or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high …

2-Amino-1, 3, 4-thiadiazole as a potential scaffold for promising antimicrobial agents

G Serban, O Stanasel, E Serban… - Drug design, development …, 2018 - Taylor & Francis
Pathogenic microorganisms are causative agents for different types of serious and even
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …

Heterocyclic scaffolds: centrality in anticancer drug development

I Ali, M Nadeem Lone, ZA Al-Othman… - Current drug …, 2015 - ingentaconnect.com
Cancer has been cursed for human beings for long time. Millions people lost their lives due
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …

Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update

K Laxmikeshav, P Kumari… - Medicinal Research …, 2022 - Wiley Online Library
This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

[HTML][HTML] Biomedical applications of selective metal complexes of indole, benzimidazole, benzothiazole and benzoxazole: A review (From 2015 to 2022)

AA Al Awadh - Saudi Pharmaceutical Journal, 2023 - Elsevier
Indole, benzoxazole benzothiazole and benzimidazole are excellent classes of organic
heterocyclic compounds. These compounds show significant application in pharmacy …

A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors

W Liu, M He, Y Li, Z Peng, G Wang - Journal of enzyme inhibition …, 2022 - Taylor & Francis
Microtubules play an important role in the process of cell mitosis and can form a spindle in
the mitotic prophase of the cell, which can pull chromosomes to the ends of the cell and then …

Novel benzothiazole-based dual VEGFR-2/EGFR inhibitors targeting breast and liver cancers: Synthesis, cytotoxic activity, QSAR and molecular docking studies

EA Abd El-Meguid, AM Naglah, GO Moustafa… - Bioorganic & Medicinal …, 2022 - Elsevier
A novel series of benzothiazole-based derivatives linked to various amino acids and their
corresponding ethyl ester analogues were prepared and were initially evaluated for their …