Clinical usefulness of autoantibodies to M-type phospholipase A2 receptor (PLA2R) for monitoring disease activity in idiopathic membranous nephropathy (IMN)

A Radice, B Trezzi, U Maggiore, F Pregnolato… - Autoimmunity …, 2016 - Elsevier
Autoantibodies to M-type phospholipase A2 receptor (PLA2R) are specific markers of
idiopathic membranous nephropathy (IMN). They can differentiate IMN from other …

New insights into immune mechanisms underlying response to Rituximab in patients with membranous nephropathy: a prospective study and a review of the literature

D Roccatello, S Sciascia, D Di Simone, L Solfietti… - Autoimmunity …, 2016 - Elsevier
Background Idiopathic membranous nephropathy (MN) is a common immune-mediated
glomerular disease and the main cause of nephrotic syndrome (NS) in Caucasian adults …

Prevalence of enhanced granular expression of thrombospondin type-1 domain-containing 7A in the glomeruli of Japanese patients with idiopathic membranous …

T Iwakura, N Ohashi, A Kato, S Baba, H Yasuda - PloS one, 2015 - journals.plos.org
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults.
Autoantibodies against M-type phospholipase A2 receptor (PLA2R) and thrombospondin …

Diagnostic accuracy of PLA2R autoantibodies and glomerular staining for the differentiation of idiopathic and secondary membranous nephropathy: an updated meta …

H Dai, H Zhang, Y He - Scientific reports, 2015 - nature.com
The diagnostic performance of M-type phospholipase A2 receptor (PLA2R) autoantibodies
and PLA2R glomerular staining in discriminating between idiopathic membranous …

Retrospective study of phospholipase A2 receptor and IgG subclasses in glomerular deposits in Chinese patients with membranous nephropathy

H Dong, Y Wang, X Cheng, G Wang, L Sun, H Cheng… - PLoS …, 2016 - journals.plos.org
Background and objectives The research work in the past years showed that detection of
phospholipase A2 receptor (PLA2R) antigen and its dominant IgG4 autoantibody in …

Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: a cross-sectional study

L Pang, AM Zhang, HX Li, JL Du, LL Jiao, N Duan… - Medicine, 2017 - journals.lww.com
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary
membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of …

[HTML][HTML] Diagnostic test accuracy of serum anti-PLA2R autoantibodies and glomerular PLA2R antigen for diagnosing idiopathic membranous nephropathy: an …

W Li, Y Zhao, P Fu - Frontiers in Medicine, 2018 - frontiersin.org
Background: M-type phospholipase A2 Receptor is known as a major antigen on podocytes
which is involved with the pathogenesis of idiopathic membranous nephropathy (iMN). Many …

Ultrasensitive quantitation of anti-phospholipase A2 receptor antibody as a diagnostic and prognostic indicator of idiopathic membranous nephropathy

Q Zhang, B Huang, X Liu, B Liu, Y Zhang, Z Zhang… - Scientific Reports, 2017 - nature.com
Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful for affirming the diagnosis of
idiopathic membranous nephropathy (IMN). Time-resolved fluoroimmunoassay (TRFIA) is …

[HTML][HTML] Phospholipase A2 receptor antibody IgG4 subclass improves sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy

B Huang, Y Zhang, L Wang, W Xu, J Zhang… - Kidney and Blood …, 2019 - karger.com
Aims: The aim of this study was to develop a new method for detecting anti-phospholipase
A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic …

A novel time-resolved fluoroimmunoassay for the quantitative detection of antibodies against the phospholipase A2 receptor

B Huang, L Wang, Y Zhang, J Zhang, Q Zhang… - Scientific reports, 2017 - nature.com
A highly sensitive time-resolved fluoroimmunoassay (TRFIA) was developed to quantify
serum antibodies against the phospholipase A2 receptor (anti-PLA2R-IgG) for differential …