[HTML][HTML] Lipid droplet biogenesis and functions in health and disease
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
[HTML][HTML] Apolipoprotein B and cardiovascular disease: biomarker and potential therapeutic target
J Behbodikhah, S Ahmed, A Elyasi, LJ Kasselman… - Metabolites, 2021 - mdpi.com
Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank
Cardiometabolic diseases are the leading cause of death worldwide. Despite a known
genetic component, our understanding of these diseases remains incomplete. Here, we …
genetic component, our understanding of these diseases remains incomplete. Here, we …
[HTML][HTML] Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017
AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
[HTML][HTML] BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states
J Beumer, J Puschhof, FY Yengej, L Zhao… - Cell Reports, 2022 - cell.com
Intestinal epithelial cells derive from stem cells at the crypt base and travel along the crypt-
villus axis to die at the villus tip. The two dominant villus epithelial cell types, absorptive …
villus axis to die at the villus tip. The two dominant villus epithelial cell types, absorptive …
Non-HDL-cholesterol and apolipoprotein B compared with LDL-cholesterol in atherosclerotic cardiovascular disease risk assessment
SS Carr, AJ Hooper, DR Sullivan, JR Burnett - Pathology, 2019 - Elsevier
Low density lipoprotein (LDL) is the predominant atherogenic lipoprotein particle in the
circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic …
circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic …
[HTML][HTML] Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears
Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic
physiological changes in response to Arctic climates and a hyperlipid diet of primarily …
physiological changes in response to Arctic climates and a hyperlipid diet of primarily …
Familial hypercholesterolemia treatments: Guidelines and new therapies
Familial hypercholesterolemia (FH) is a genetic disorder resulting from mutations in genes
encoding proteins involved in the metabolism of low density lipoproteins (LDL) and …
encoding proteins involved in the metabolism of low density lipoproteins (LDL) and …
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease
A Helgadottir, S Gretarsdottir, G Thorleifsson… - Nature …, 2016 - nature.com
Sequence variants affecting blood lipids and coronary artery disease (CAD) may enhance
understanding of the atherogenicity of lipid fractions. Using a large resource of whole …
understanding of the atherogenicity of lipid fractions. Using a large resource of whole …
Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial …
PN Hopkins, PP Toth, CM Ballantyne… - Journal of clinical …, 2011 - Elsevier
Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening
recommendations from the National Lipid Association Expert Panel on Familial …
recommendations from the National Lipid Association Expert Panel on Familial …