Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Drug screening at single-organoid resolution via bioprinting and interferometry

PJ Tebon, B Wang, AL Markowitz, A Davarifar… - Nature …, 2023 - nature.com
High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers

A Marzi, KM Eder, Á Barroso, AM Wågbø… - Drug delivery and …, 2022 - Springer
State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes
and several staining steps which can be affected by nanomaterial interference. Digital …

[HTML][HTML] Fabrication and validation of an LED array microscope for multimodal, quantitative imaging

TE Moustafa, ER Polanco, RL Belote… - HardwareX, 2023 - Elsevier
The combination of multiple imaging modalities in a single microscopy system can enable
new insights into biological processes. In this work, we describe the construction and …

Establishing a reference focal plane using beads for trypan‐blue‐based viability measurements

A Peskin, SP Lund, L Pierce, F Kurbanov… - Journal of …, 2021 - Wiley Online Library
Trypan blue dye exclusion‐based cell viability measurements are highly dependent upon
image quality and consistency. In order to make measurements repeatable, one must be …