Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …

Pt (II)-thiocarbohydrazone complex as cytotoxic agent and apoptosis inducer in Caov-3 and HT-29 Cells through the P53 and caspase-8 pathways

AA Ibrahim, MM Kareem, TH Al-Noor, T Al-Muhimeed… - Pharmaceuticals, 2021 - mdpi.com
In this study, a platinum (II) complex ([Pt (H2L)(PPh3)] complex) containing a
thiocarbohydrazone as the ligand was tested as an anti-proliferative agent against ovarian …

Novel of nano delivery system for Linalool loaded on gold nanoparticles conjugated with CALNN peptide for application in drug uptake and induction of cell death on …

MS Jabir, AA Taha, UI Sahib, ZJ Taqi… - Materials science and …, 2019 - Elsevier
Linalool is a monoterpene alcohol which occurs naturally in several aromatic plants. The
aims of this study are to load Linalool on gold nanoparticles, conjugate the complex with …

[HTML][HTML] Biodistribution of gadolinium-and near infrared-labeled human umbilical cord mesenchymal stromal cell-derived exosomes in tumor bearing mice

J Abello, TDT Nguyen, R Marasini, S Aryal… - Theranostics, 2019 - ncbi.nlm.nih.gov
We speculate that exosomes derived from human umbilical cord mesenchymal stromal cells
(HUC-MSCs) will accumulate within tumors and have the potential for both tumor location or …

Gold nanoparticles loaded into niosomes: A novel approach for enhanced antitumor activity against human ovarian cancer

FR Amale, S Ferdowsian, S Hajrasouliha… - Advanced Powder …, 2021 - Elsevier
In the current study, gold nanoparticles (AuNPs) were prepared using the green synthesis
method using Artemisia annua extract, loaded into niosomes, and investigated their …

Gold nanoparticles loaded TNF-α and CALNN peptide as a drug delivery system and promising therapeutic agent for breast cancer cells

MS Jabir, NA Abood, MH Jawad, K Öztürk… - Materials …, 2022 - Taylor & Francis
We investigated the anti-cancer properties of gold nanoparticles loaded TNF-and CALNN
peptides, which we proposed as a potential drug delivery system using in vitro and in vivo …

Triphenylphosphonium conjugated gold nanotriangles impact Pi3K/AKT pathway in breast cancer cells: a photodynamic therapy approach

NM Vinita, U Devan, S Durgadevi, S Anitha… - Scientific Reports, 2023 - nature.com
Although gold nanoparticles based photodynamic therapy (PDT) were reported to improve
efficacy and specificity, the impact of surface charge in targeting cancer is still a challenge …

Neuroprotective role of hyperforin on aluminum maltolate-induced oxidative damage and apoptosis in PC12 cells and SH-SY5Y cells

H Wang, B Shao, H Yu, F Xu, P Wang, K Yu… - Chemico-biological …, 2019 - Elsevier
Many reports demonstrated that aluminum maltolate (Almal) has potential toxicity to human
and animal. Our study has demonstrated that Almal can induce oxidative damage and …

ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and …

J Fu, X Chen, X Liu, D Xu, H Yang, C Zeng… - Stem Cell Research & …, 2020 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have exerted their brilliant potential to
promote heart repair following myocardial infarction. However, low survival rate of MSCs …