Ferritin is one of the most frequently requested laboratory tests in primary and secondary
care, and levels often deviate from reference ranges. Serving as an indirect marker for total …

The definition 'iron loading anaemias' encompasses a group of inherited and acquired
anaemias characterized by ineffective erythropoiesis, low hepcidin levels, excessive iron …

New insights into iron regulation and erythropoiesis : Current Opinion in Hematology New
insights into iron regulation and erythropoiesis : Current Opinion in Hematology Log in or …

Multiple human diseases ensue from a hereditary or acquired deficiency of iron-transporting
protein function that diminishes transmembrane iron flux in distinct sites and directions …

Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent.
Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate …

Although iron is vital, its free form is likely to be involved in oxidation-reduction reactions,
leading to the formation of free radicals and oxidative stress. Living organisms have …

Among the different mechanisms involved in oxidative stress, protein carbonylation and lipid
peroxidation are both important modifications associated with the pathogenesis of several …

Erythropoietin (EPO) is the main hormone regulating red blood cell (RBC) production. The
large-scale production of a recombinant human erythropoietin (rHuEPO) by biotechnological …

Thymosin β4 (Tβ4) was extracted forty years agofrom calf thymus. Since then, it has been
identified as a G-actin binding protein involved in blood clotting, tissue regeneration …

Iron, although essential, is harmful in high amounts. Oxidative stress as a result of excess
reactive oxygen species (ROS) and a prooxidative/antioxidative imbalance between ROS …