Development of reporter gene assays to determine the bioactivity of biopharmaceuticals

L Wang, C Yu, J Wang - Biotechnology advances, 2020 - Elsevier
Complex structure and structure-function relationship of biopharmaceuticals require
extensive analytical characterization and appropriate quality control of the products. Despite …

[HTML][HTML] Biochemical characterization, cytotoxic, antimutagenic, anticancer and molecular docking studies on Tecomella undulata

S Riaz, MA Javed, I Nawaz, T Javed - Saudi Journal of Biological Sciences, 2022 - Elsevier
In this study bioassay-guided screening of Tecomella undulate was performed for its
cytotoxic, antimutagenic and anticancer potential. The ariel parts were extracted on a …

Systemic optimization of gene electrotransfer protocol using hard-to-transfect UT-7 cell line as a model

R Vadeikienė, B Jakštys, R Ugenskienė, S Šatkauskas… - Biomedicines, 2022 - mdpi.com
Non-adherent cells are difficult to transfect with chemical-mediated delivery methods.
Electroporation is an attractive strategy to transfer the molecules of interest into suspension …

3r's applied to in vivo biological activity of recombinant human erythropoietin assay

AP Arevalo, T Basika, S Ancheta… - Biological Models …, 2023 - bmrtsbcaljournal.com
An enhanced protocol for the evaluation of in vivo biological activity of recombinant human
erythropoietin (rhEPO) assay in mice is described, following European Pharmacopoeia (Ph …

Development of in-vitro bio-assay for The bioactivity determination of human Erythropoietin (rHuEPO) bio-pharmaceutical products (November 2020-August 2021)

AS Lamia - 2021 - dspace.bracu.ac.bd
Erythropoietin is mainly secreted by the kidney and involved in the growth and maturation of
erythroid cells from precursors (Jelkmann, et al, 2013). Insufficient production of EPO could …

[PDF][PDF] СТАНДАРТИЗАЦИЯ МЕТОДИКИ ОПРЕДЕЛЕНИЯ СПЕЦИФИЧЕСКОЙ АКТИВНОСТИ ЭРИТРОПОЭТИНА

ВА Меркулов - gabrich.ru
Эритропоэтин–это цитокин, который стимулирует эритропоэз при взаимодействии с
рецепторами на клетках-предшественниках костного мозга [93]. Лекарственные …

[PDF][PDF] Faculty Profile

MN Srinivasan - 2008 - ctuap.ac.in
7. Manoj Kumar M, Vasavi M, T. Srinivasan, Uma V, Raj Kumar K.,“Development of an in
vitro bioassay for recombinant human erythropoietin (rHuEPO) based on proliferative …