[HTML][HTML] Insights into the secretome of mesenchymal stem cells and its potential applications

S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …

Key transcription factors in the differentiation of mesenchymal stem cells

SG Almalki, DK Agrawal - Differentiation, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells that represent a promising source for
regenerative medicine. MSCs are capable of osteogenic, chondrogenic, adipogenic and …

Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

[HTML][HTML] Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis

WC Zhang, N Shyh-Chang, H Yang, A Rai… - Cell, 2012 - cell.com
Identification of the factors critical to the tumor-initiating cell (TIC) state may open new
avenues in cancer therapy. Here we show that the metabolic enzyme glycine decarboxylase …

Fibroblasts and mesenchymal stromal/stem cells are phenotypically indistinguishable

RA Denu, S Nemcek, DD Bloom, A Goodrich, J Kim… - Acta …, 2016 - karger.com
Background/Aims: Human mesenchymal stromal/stem cells (MSCs), derived from many
different tissues, are characterized by a fibroblast-like morphology, the expression of certain …

Paracrine mechanisms of stem cell reparative and regenerative actions in the heart

M Mirotsou, TM Jayawardena, J Schmeckpeper… - Journal of molecular and …, 2011 - Elsevier
Stem cells play an important role in restoring cardiac function in the damaged heart. In order
to mediate repair, stem cells need to replace injured tissue by differentiating into specialized …

Fibroblasts and mesenchymal stem cells: Two sides of the same coin?

M Soundararajan, S Kannan - Journal of cellular physiology, 2018 - Wiley Online Library
Mesenchymal stem/stromal cells (MSCs) have gained considerable popularity owing to the
vast possibilities and lack of ethical constraints and risks normally associated with other …

Culture media for the differentiation of mesenchymal stromal cells

C Vater, P Kasten, M Stiehler - Acta biomaterialia, 2011 - Elsevier
Mesenchymal stromal cells (MSCs) can be isolated from various tissues such as bone
marrow aspirates, fat or umbilical cord blood. These cells have the ability to proliferate in …

Postischemic revascularization: from cellular and molecular mechanisms to clinical applications

JS Silvestre, DM Smadja, BI Levy - Physiological reviews, 2013 - journals.physiology.org
After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

[HTML][HTML] Stem cells and cell therapies in lung biology and lung diseases

DJ Weiss, I Bertoncello, Z Borok, C Kim… - Proceedings of the …, 2011 - atsjournals.org
EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …