Multipotent neural stem cells are present throughout the development of the central nervous
system (CNS), persist into adulthood in defined locations and can be derived from more …

Polysialic acid (PSA) is a linear homopolymer of α2-8-N acetylneuraminic acid whose major
carrier in vertebrates is the neural cell adhesion molecule (NCAM). PSA serves as a potent …

After central nervous system (CNS) demyelination—such as occurs during multiple sclerosis—
there is often spontaneous regeneration of myelin sheaths, mainly by oligodendrocytes but …

Demyelination contributes to loss of function after spinal cord injury, and thus a potential
therapeutic strategy involves replacing myelin-forming cells. Here, we show that …

We report that prospectively isolated, human CNS stem cells grown as neurospheres (hCNS-
SCns) survive, migrate, and express differentiation markers for neurons and …

We have previously isolated, expanded, and characterized a multipotent precursor cell from
mammalian dermis (termed skin‐derived precursors [SKPs]) that can differentiate into both …

Remyelination is the regenerative process by which demyelinated axons are reinvested with
new myelin sheaths. It is associated with functional recovery and maintenance of axonal …

The spinal cord is part of the central nervous system (CNS) and serves to connect the brain
to the peripheral nervous system and peripheral tissues. The cell types that primarily …

During brain ontogenesis, the temporal and spatial generation of the different types of
neuronal and glial cells from precursors occurs as a sequence of successive progenitor …

Bone marrow contains a population of stem-like cells that can differentiate into neurons or
glia. Stromal cells from green fluorescent protein (GFP)-expressing mice were isolated by …